Despite the availabilty of imaging-based and mass-spectrometry-based methods for spatial
proteomics, a key challenge remains connecting images with single-cell-resolution protein …

Metastatic melanoma is the most aggressive and difficult to treat type of skin cancer, with a
survival rate of less than 10%. Metastatic melanoma has conventionally been considered …

Cell adhesion molecules (CAMs) of the cadherin, integrin, immunoglobulin, and selectin
protein families are indispensable for the formation and maintenance of multicellular tissues …

Background & Aims Cancer-associated fibroblasts (CAFs) play an important role in
colorectal cancer (CRC) progression and predict poor prognosis in CRC patients. However …

Precise detection of early melanomas is essential as the stage of disease guides treatment
options. One growing field that may facilitate the advancement of early melanoma detection …

Abstract Background Mesenchymal stromal cells (MSCs) and their extracellular vesicles
(MSC-EVs) have demonstrated to elicit immunomodulatory and pro-regenerative properties …

Background Human mesenchymal stem cells from dental pulp (hMSC-DP), including dental
pulp stem cells from permanent teeth and exfoliated deciduous teeth, possess unique MSC …

The trafficking of autoreactive leucocytes across the blood–brain barrier endothelium is a
hallmark of multiple sclerosis pathogenesis. Although the blood–brain barrier endothelium …

As one of the main tumor-infiltrating immune cell types, tumor-associated macrophages
(TAMs) determine the efficacy of immunotherapy. However, limited knowledge about their …

Radiotherapy is an indispensable modality in comprehensive treatment of breast cancer.
However, inherent or acquired radiation resistance of tumors compromises the efficacy of …