Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

The Janus kinase/signal transduction and activator of transcription (JAK–STAT) signaling
pathway is implicated in the pathogenesis of inflammatory and autoimmune diseases …

Whereas the cellular and molecular features of human inflammatory skin diseases are well
characterized, their tissue context and systemic impact remain poorly understood. We thus …

Cytokines, many of which signal through the JAK–STAT (Janus kinase–Signal Transducers
and Activators of Transcription) pathway, play a central role in the pathogenesis of …

Objective To examine the efficacy of methotrexate monotherapy relative to etanercept
monotherapy and the value of combining methotrexate and etanercept for the treatment of …

Abstract Summary The National Bone Health Alliance (NBHA) recommends standardized
sample handling and patient preparation for C-terminal telopeptide of type I collagen (CTX-I) …

Psoriasis is a chronic systemic inflammatory disease causing erythematosus and scaly skin
plaques; up to 30% of patients with psoriasis develop Psoriatic Arthritis (PsA), which is …

Rheumatoid arthritis (RA) and psoriatic arthritis (PsA) have key differences in clinical
presentation, radiographic findings, comorbidities and pathogenesis to distinguish between …

Aims To determine the risk of venous thromboembolism (VTE) defined as the combined
endpoint of deep venous thrombosis (DVT) and pulmonary embolism (PE) among patients …

Psoriatic arthritis (PsA) is a complex chronic musculoskeletal condition that occurs in~ 30%
of psoriasis patients. Currently, no systematic strategy is available that utilizes the …