Associations of GATA4 genetic mutations with the risk of congenital heart disease: a meta-analysis

Y Zhang, F Ai, J Zheng, B Peng - Medicine, 2017 - journals.lww.com
Background: GATA4 gene is a cardiac transcriptional factor playing important role in cardiac
formation and development. Three GATA4 gene mutations, 99 G> T, 487 C> T, and 354 A> …

[HTML][HTML] Insights into role of microRNAs in cardiac development, cardiac diseases, and developing novel therapies

M Arabian, FM Azad, M Maleki… - Iranian Journal of Basic …, 2020 - ncbi.nlm.nih.gov
Materials and Methods: We reviewed published research on association and role of miRNAs
in cardiac development and diseases and investigated the possible links between …

[HTML][HTML] GATA5 loss-of-function mutations underlie tetralogy of fallot

D Wei, H Bao, XY Liu, N Zhou, Q Wang… - … journal of medical …, 2013 - ncbi.nlm.nih.gov
Tetraology of Fallot (TOF) is the most common form of cyanotic congenital heart disease and
is a major cause of significant morbidity and mortality. Emerging evidence demonstrates that …

Prevalence and spectrum of GATA5 mutations associated with congenital heart disease.

JQ Jiang, RG Li, J Wang, XY Liu, YJ Xu… - … journal of cardiology, 2012 - europepmc.org
Prevalence and spectrum of GATA5 mutations associated with congenital heart disease. -
Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About …

GATA5 Loss-of-Function Mutation Responsible for the Congenital Ventriculoseptal Defect

D Wei, H Bao, N Zhou, GF Zheng, XY Liu, YQ Yang - Pediatric cardiology, 2013 - Springer
The ventriculoseptal defect (VSD) is the most common form of congenital heart disease and
a leading noninfectious cause of infant mortality. Growing evidence demonstrates that …

Identification of dysfunctional modules and disease genes in congenital heart disease by a network-based approach

D He, ZP Liu, L Chen - BMC genomics, 2011 - Springer
Background The incidence of congenital heart disease (CHD) is continuously increasing
among infants born alive nowadays, making it one of the leading causes of infant morbidity …

Functional study of DAND5 variant in patients with congenital heart disease and laterality defects

F Cristo, JM Inácio, S de Almeida, P Mendes… - BMC medical …, 2017 - Springer
Abstract Background Perturbations on the Left-Right axis establishment lead to laterality
defects, with frequently associated Congenital Heart Diseases (CHDs). Indeed, in the last …

Somatic mutations in the GATA6 gene underlie sporadic tetralogy of Fallot

RT Huang, S Xue, YJ Xu… - … journal of molecular …, 2013 - spandidos-publications.com
Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease associated
with significant morbidity and mortality in humans. However, the molecular etiology …

Prevalence and spectrum of PITX2c mutations associated with congenital heart disease

J Wang, YF Xin, WJ Xu, ZM Liu, XB Qiu, XK Qu… - DNA and cell …, 2013 - liebertpub.com
Congenital heart disease (CHD) is the most common form of birth defect and is the leading
noninfectious cause of infant death. A growing body of evidence demonstrates that genetic …

Somatic GATA5 mutations in sporadic tetralogy of Fallot

RT Huang, S Xue, YJ Xu… - … journal of molecular …, 2014 - spandidos-publications.com
Tetralogy of Fallot (TOF) is the most common form of cyanotic congenital heart disease, with
high morbidity and mortality rates. Accumulating evidence has demonstrated that genetic …