From targeted methods to metabolomics based strategies to screen for growth promoters misuse in horseracing and livestock: A review
C Cloteau, Z Kaabia, B Le Bizec, L Bailly-Chouriberry… - Food Control, 2023 - Elsevier
Despite banned for public health, societal and economic reasons, and therefore strictly
regulated, growth promoters can still be used in farm animals to increase production yields …
regulated, growth promoters can still be used in farm animals to increase production yields …
Doping detection in animals: A review of analytical methodologies published from 1990 to 2019
Despite the impressive innate physical abilities of horses, camels, greyhounds, or pigeons,
doping agents might be administered to these animals to improve their performance. To …
doping agents might be administered to these animals to improve their performance. To …
[HTML][HTML] Investigations into the elimination profiles and metabolite ratios of micro-dosed selective androgen receptor modulator LGD-4033 for doping control purposes
F Wagener, S Guddat, C Görgens, YS Angelis… - Analytical and …, 2022 - Springer
Abstract LGD-4033 (ligandrol) is a selective androgen receptor modulator (SARM), which is
prohibited in sports by the World Anti-Doping Agency (WADA) and led to 62 adverse …
prohibited in sports by the World Anti-Doping Agency (WADA) and led to 62 adverse …
Identification of equine in vitro metabolites of seven non‐steroidal selective androgen receptor modulators for doping control purposes
C Cutler, M Viljanto, P Taylor, P Hincks… - Drug Testing and …, 2022 - Wiley Online Library
Selective androgen receptor modulators, SARMs, are a large class of compounds
developed to provide therapeutic anabolic effects with minimal androgenic side effects. A …
developed to provide therapeutic anabolic effects with minimal androgenic side effects. A …
Detection of the selective androgen receptor modulator GSK2881078 and metabolites in urine and hair after single oral administration
A Rading, P Anielski, D Thieme… - Drug Testing and …, 2021 - Wiley Online Library
Hair and urine concentrations of the nonsteroidal selective androgen receptor modulator
GSK2881078 were examined following single oral administration to investigate its hair …
GSK2881078 were examined following single oral administration to investigate its hair …
Long‐term monitoring of IOX4 in horse hair and its longitudinal distribution with segmental analysis using liquid chromatography/electrospray ionization Q Exactive …
H Ishii, M Shibuya, YM So, JKY Wong… - Drug Testing and …, 2022 - Wiley Online Library
IOX4, a hypoxia‐inducible factor stabilizer, is classified as a banned substance for horses in
both horse racing and equestrian sports. We recently reported the pharmacokinetic profiles …
both horse racing and equestrian sports. We recently reported the pharmacokinetic profiles …
[HTML][HTML] Structure revision and chemical synthesis of ligandrol's main bishydroxylated long-term metabolic marker
EN Pitsinos, YS Angelis, M Petrou - Organic & Biomolecular Chemistry, 2022 - pubs.rsc.org
Although the main bishydroxylated long-term metabolite of the WADA-banned anabolic
agent ligandrol (LGD-4033) is an important metabolic marker, it is not readily available in …
agent ligandrol (LGD-4033) is an important metabolic marker, it is not readily available in …
[HTML][HTML] Investigations into the concentration and metabolite profiles of stanozolol and LGD-4033 in blood plasma and seminal fluid using liquid chromatography high …
J Breuer, A Thomas, P Delahaut, W Schänzer… - Analytical and …, 2023 - Springer
Potential scenarios as to the origin of minute amounts of banned substances detected in
doping control samples have been a much-discussed problem in anti-doping analysis in …
doping control samples have been a much-discussed problem in anti-doping analysis in …
Metabolic studies of selective androgen receptor modulators RAD140 and S‐23 in horses
YM So, JKY Wong, TLS Choi, A Prabhu… - Drug Testing and …, 2021 - Wiley Online Library
This paper describes the studies of the in vitro biotransformation of two selective androgen
receptor modulators (SARMs), namely, RAD140 and S‐23, and the in vivo metabolism of …
receptor modulators (SARMs), namely, RAD140 and S‐23, and the in vivo metabolism of …
Equine metabolism of the selective androgen receptor modulator YK‐11 in urine and plasma following oral administration
C Harding, M Viljanto… - Drug Testing and …, 2023 - Wiley Online Library
YK‐11 is a steroidal selective androgen receptor modulator, a compound class prohibited in
both equine racing and human sports because of their potentially performance enhancing …
both equine racing and human sports because of their potentially performance enhancing …