[HTML][HTML] Polyphenols and their applications: An approach in food chemistry and innovation potential

FF de Araújo, D de Paulo Farias, IA Neri-Numa… - Food chemistry, 2021 - Elsevier
Polyphenols are compounds naturally present in fruits and vegetables that are gaining more
and more attention due to their therapeutic effects and their potential technological …

Anti-inflammatory and active biological properties of the plant-derived bioactive compounds luteolin and luteolin 7-glucoside

S Caporali, A De Stefano, C Calabrese, A Giovannelli… - Nutrients, 2022 - mdpi.com
Flavonoids are interesting molecules synthetized by plants. They can be found abundantly
in seeds and fruits, determining the color, flavor, and other organoleptic characteristics, as …

[HTML][HTML] Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration

K Kaarniranta, H Uusitalo, J Blasiak… - Progress in retinal and …, 2020 - Elsevier
Oxidative stress-induced damage to the retinal pigment epithelium (RPE) is considered to
be a key factor in age-related macular degeneration (AMD) pathology. RPE cells are …

Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies

N Aziz, MY Kim, JY Cho - Journal of ethnopharmacology, 2018 - Elsevier
Abstract Ethnopharmacological relevance Luteolin (3′, 4′, 5, 7-tetrahydroxyflavone) has
been identified as commonly present in plants. Plants with a high luteolin content have been …

Dietary polyphenols in age‐related macular degeneration: protection against oxidative stress and beyond

E Pawlowska, J Szczepanska… - Oxidative medicine …, 2019 - Wiley Online Library
Age‐related macular degeneration (AMD) is a multifactorial disease of the retina featured by
degeneration and loss of photoreceptors and retinal pigment epithelium (RPE) cells with …

[HTML][HTML] Polyphenols Targeting NF-κB Pathway in Neurological Disorders: What We Know So Far?

A Al Mamun, C Shao, P Geng, S Wang… - International Journal of …, 2024 - ncbi.nlm.nih.gov
Polyphenolic compounds have shown promising neuroprotective properties, making them a
valuable resource for identifying prospective drug candidates to treat several neurological …

A comprehensive review of natural flavonoids with anti-SARS-CoV-2 activity

JY Yang, YX Ma, Y Liu, XJ Peng, XZ Chen - Molecules, 2023 - mdpi.com
The COVID-19 pandemic caused by SARS-CoV-2 has majorly impacted public health and
economies worldwide. Although several effective vaccines and drugs are now used to …

Effect of fisetin supplementation on inflammatory factors and matrix metalloproteinase enzymes in colorectal cancer patients

A Farsad-Naeimi, M Alizadeh, A Esfahani… - Food & function, 2018 - pubs.rsc.org
A growing body of evidence indicates that inflammation is associated with tumorigenesis,
metastasis and chemotherapeutic resistance in patients with colorectal cancer (CRC) …

Fisetin inhibits proliferation of pancreatic adenocarcinoma by inducing DNA damage via RFXAP/KDM4A-dependent histone H3K36 demethylation

G Ding, X Xu, D Li, Y Chen, W Wang, D Ping… - Cell Death & …, 2020 - nature.com
Pancreatic adenocarcinoma (PDAC) is an extremely malignant tumor that is associated with
low survival rates. Fisetin is a natural flavonoid that shows diverse antitumor effects …

Luteolin Attenuates IL‐1β‐Induced THP‐1 Adhesion to ARPE‐19 Cells via Suppression of NF‐κB and MAPK Pathways

WC Huang, CJ Liou, SC Shen, S Hu… - Mediators of …, 2020 - Wiley Online Library
Cytokine‐induced endothelial dysfunction leads to inflammation and vascular adhesion
molecule production in retinal pigment epithelium (RPE) cells. Inflammation is a critical …