Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research
DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …
behavior have steadily increased over the last two decades, stimulating considerable …
Roles of oxytocin in stress responses, allostasis and resilience
Y Takayanagi, T Onaka - International journal of molecular sciences, 2021 - mdpi.com
Oxytocin has been revealed to work for anxiety suppression and anti-stress as well as for
psychosocial behavior and reproductive functions. Oxytocin neurons are activated by …
psychosocial behavior and reproductive functions. Oxytocin neurons are activated by …
The correlation between central and peripheral oxytocin concentrations: a systematic review and meta-analysis
M Valstad, GA Alvares, M Egknud… - Neuroscience & …, 2017 - Elsevier
There is growing interest in the role of the oxytocin system in social cognition and behavior.
Peripheral oxytocin concentrations are regularly used to approximate central concentrations …
Peripheral oxytocin concentrations are regularly used to approximate central concentrations …
Kinetics and dose dependency of intranasal oxytocin effects on amygdala reactivity
Background Current neuroimaging perspectives on a variety of mental disorders emphasize
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …
A registered replication study on oxytocin and trust
In an influential paper, Kosfeld et al.(2005) showed that intranasal administration of oxytocin
(OT) increases the transfers made by investors in the trust game—suggesting that OT …
(OT) increases the transfers made by investors in the trust game—suggesting that OT …
Nose-to-brain peptide delivery–the potential of nanotechnology
E Samaridou, MJ Alonso - Bioorganic & medicinal chemistry, 2018 - Elsevier
Abstract Nose-to-brain (N-to-B) delivery offers to protein and peptide drugs the possibility to
reach the brain in a non-invasive way. This article is a comprehensive review of the state-of …
reach the brain in a non-invasive way. This article is a comprehensive review of the state-of …
Oxytocin and brain activity in humans: a systematic review and coordinate-based meta-analysis of functional MRI studies
SA Grace, SL Rossell, M Heinrichs… - …, 2018 - Elsevier
Oxytocin (OXT) is a neuropeptide which has a critical role in human social behaviour and
cognition. Research investigating the role of OXT on functional brain changes in humans …
cognition. Research investigating the role of OXT on functional brain changes in humans …
Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans
DA Martins, N Mazibuko, F Zelaya… - Nature …, 2020 - nature.com
Could nose-to-brain pathways mediate the effects of peptides such as oxytocin (OT) on brain
physiology when delivered intranasally? We address this question by contrasting two …
physiology when delivered intranasally? We address this question by contrasting two …
Sniffing oxytocin: Nose to brain or nose to blood?
S Yao, Y Chen, Q Zhuang, Y Zhang, C Lan, S Zhu… - Molecular …, 2023 - nature.com
In recent years ample studies have reported that intranasal administration of the
neuropeptide oxytocin can facilitate social motivation and cognition in healthy and clinical …
neuropeptide oxytocin can facilitate social motivation and cognition in healthy and clinical …
Nanotechnologies for intranasal drug delivery: an update of literature
R Lombardo, T Musumeci, C Carbone… - Pharmaceutical …, 2021 - Taylor & Francis
Scientific research has focused its attention on finding an alternative route to systemic oral
and parenteral administration, to overcome their usual drawbacks, such as hepatic first-pass …
and parenteral administration, to overcome their usual drawbacks, such as hepatic first-pass …