Unbiased allele transmission into progeny is a fundamental genetic concept canonized as
Mendel's Law of Segregation. Not all alleles, however, abide by the law. Killer meiotic …

Reproductive isolation is both an indicator of speciation and a mechanism for maintaining
species identity. Here we review the progress in studies of hybrid sterility in rice to illustrate …

Several features of the yeast mitochondrial genome, including high mutation rate, dynamic
genomic structure, small effective population size, and dispensability for cellular viability …

Meiotic drive causes the distortion of allelic segregation away from Mendelian expected
ratios, often also reducing fecundity and favouring the evolution of drive suppressors. If …

Large blocks of tandemly repeated DNAs—satellite DNAs (satDNAs)—play important roles
in heterochromatin formation and chromosome segregation. We know little about how …

Widespread loss of genes on the Y is considered a hallmark of sex chromosome
differentiation. Here we show that the initial stages of Y evolution are driven by massive …

Y chromosomes are typically viewed as genetic wastelands with few intact genes. Recent
genomic analyses in Drosophila, however, show that gene gain is prominent on young Y …

The separation of germ cell populations from the soma is part of the evolutionary transition to
multicellularity. Only genetic information present in the germ cells will be inherited by future …

Y chromosomes often contain amplified genes which can increase dosage of male fertility
genes and counteract degeneration via gene conversion. Here we identify genes with …

Although the biological utilities of endogenous RNAi (endo-RNAi) have been largely
elusive, recent studies reveal its critical role in the non-model fruitfly Drosophila simulans to …