[HTML][HTML] Recent miRNA research in asthma

R Sharma, A Tiwari, MJ McGeachie - Current allergy and asthma reports, 2022 - Springer
Abstract Purpose of Review The study of microRNA in asthma has revealed a vibrant new
level of gene regulation underlying asthma pathology. Several miRNAs have been shown to …

[HTML][HTML] “Liquid biopsy”-extracellular vesicles as potential novel players towards precision medicine in asthma

D Ambrożej, A Stelmaszczyk-Emmel… - Frontiers in …, 2022 - frontiersin.org
Extracellular vesicles (EVs) have emerged as vital mediators in intracellular communication
in the lung microenvironment. Environmental exposure to various triggers (eg, viruses …

[HTML][HTML] MiRNA and exosomal miRNA as new biomarkers useful to phenotyping severe asthma

P Soccio, G Moriondo, D Lacedonia, P Tondo… - Biomolecules, 2023 - mdpi.com
Severe asthma (SA) is a chronic inflammatory disease of the airways. Due to the extreme
heterogeneity of symptoms, new biomarkers are currently needed. MiRNAs are non-coding …

[HTML][HTML] Extracellular vesicles from immune cells: A biomedical perspective

MJ Moya-Guzmán, J de Solminihac, C Padilla… - International Journal of …, 2023 - mdpi.com
Research on the role of extracellular vesicles (sEV) in physiology has demonstrated their
undoubted importance in processes such as the transportation of molecules with …

MicroRNA-21-5p promotes mucosal type 2 inflammation via regulating GLP1R/IL-33 signaling in chronic rhinosinusitis with nasal polyps

G Luan, M Wang, J Yuan, X Bu, Y Wang, S Ying… - Journal of Allergy and …, 2022 - Elsevier
Background It has been known that chronic rhinosinusitis with nasal polyps (CRSwNP) is a
type 2 inflammation–dominated disease; however, the reasons causing such type of …

[HTML][HTML] The Roles of MicroRNAs in Asthma and Emerging Insights into the Effects of Vitamin D3 Supplementation

A Hernández-Díazcouder, R Romero-Nava… - Nutrients, 2024 - mdpi.com
Asthma is one of the most common chronic non-communicable diseases worldwide,
characterized by variable airflow limitation secondary to airway narrowing, airway wall …

MiR-506 targets polypyrimidine tract-binding protein 1 to inhibit airway inflammatory response and remodeling via mediating Wnt/β-catenin signaling pathway

Y Cai, J Tian, Y Su, X Shi - Allergologia et Immunopathologia, 2023 - all-imm.com
Background: Airway remodeling, which contributes to the clinical course of childhood
asthma, occurs due to airway inflammation and is featured by anomalous biological …

Exosomes in asthma: Underappreciated contributors to the pathogenesis and novel therapeutic tools

Z Kanannejad, S Arab, S Soleimanian… - Immunity …, 2024 - Wiley Online Library
Objective Asthma, a chronic inflammatory disease with diverse pathomechanisms, presents
challenges in developing personalized diagnostic and therapeutic approaches. This review …

Cysteine and glycine‐rich protein 2 retards platelet‐derived growth factor‐BB‐evoked phenotypic transition of airway smooth muscle cells by decreasing YAP/TAZ …

H Wang, Y Zhang, B Zhong, Y Geng… - Cell Biochemistry …, 2024 - Wiley Online Library
Cysteine and glycine‐rich protein 2 (Csrp2) has emerged as a key factor in controlling the
phenotypic modulation of smooth muscle cells. The phenotypic transition of airway smooth …

miR-21-5p Modulates Airway Inflammation and Epithelial-Mesenchymal Transition Processes in a Mouse Model of Combined Allergic Rhinitis and Asthma Syndrome.

Z Mao, Z Ding, Z Liu, Y Shi, Q Zhang - International Archives of …, 2024 - europepmc.org
Methods The levels of miR-21-5p and PARP-1 in CARAS patients were detected by
quantitative reverse transcription polymerase chain reaction and enzyme-linked …