Loss of α6β4-dependent hemidesmosomal adhesions has been observed during prostate
cancer progression. However, the significance and underlying mechanisms by which …

Background We have developed a gene expression assay (Whole-Genome DASL®),
capable of generating whole-genome gene expression profiles from degraded samples …

MRI is used to image prostate cancer and target tumors for biopsy or therapeutic ablation.
The objective was to understand the biology of tumors not visible on MRI that may go …

To find an association between genomic features of connective tissue and pejorative clinical
outcomes on radical prostatectomy specimens. We performed a retrospective analysis of …

microRNAs (miRNAs) are a growing class of small non-coding RNAs that exhibit
widespread dysregulation in prostate cancer. We profiled miRNA expression in syngeneic …

Molecular diagnostics is a rapidly evolving area of surgical pathology, that is gradually
beginning to transform our diagnostical procedures for a variety of tumors. Next to molecular …

Overtreatment remains a pervasive problem in prostate cancer management due to the
highly variable and often indolent course of disease. Molecular signatures derived from …

Urologic cancers include cancers of the bladder, kidney, prostate, and testes, with common
molecular features spanning different types. Here, we show that 1954 urologic cancers can …

Abstract The Tumor protein D52 (TPD52) gene was identified nearly 20 years ago through
its overexpression in human cancer, and a substantial body of data now strongly supports …

Purpose: There is a clear need to improve risk stratification and to identify novel therapeutic
targets in aggressive prostate cancer. The goal of this study was to investigate genes with …