[HTML][HTML] Radon and lung cancer: current trends and future perspectives

M Riudavets, M Garcia de Herreros, B Besse… - Cancers, 2022 - mdpi.com
Simple Summary Radon represents the main risk factor of lung cancer in non-smokers and
the second one in smoking patients. In Europe, there are several radon-prone areas, but …

[HTML][HTML] Human health impacts of residential radon exposure: updated systematic review and meta-analysis of case–control studies

LTN Ngoc, D Park, YC Lee - International Journal of Environmental …, 2022 - mdpi.com
This study investigated the impact of residential radon exposure on human cancers (ie, lung
cancer and childhood leukemia) through a systematic review and meta-analysis of case …

[HTML][HTML] AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells

H Li, Z Liu, L Liu, H Zhang, C Han, L Girard, H Park… - Cell Reports …, 2022 - cell.com
Mutations in STK11/LKB1 in non-small cell lung cancer (NSCLC) are associated with poor
patient responses to immune checkpoint blockade (ICB), and introduction of a Stk11/Lkb1 …

[HTML][HTML] Radon exposure is rising steadily within the modern North American residential environment, and is increasingly uniform across seasons

FKT Stanley, JL Irvine, WR Jacques, SR Salgia… - Scientific reports, 2019 - nature.com
Human-made buildings can artificially concentrate radioactive radon gas of geologic origin,
exposing occupants to harmful alpha particle radiation emissions that damage DNA and …

Radon exposure: a major cause of lung cancer

M Lorenzo-Gonzalez, M Torres-Duran… - Expert review of …, 2019 - Taylor & Francis
Introduction: Lung cancer is the most important cause of cancer mortality. It is a multifactorial
disease with multiple risk factors, including residential radon exposure. Areas covered: The …

[HTML][HTML] Rising Canadian and falling Swedish radon gas exposure as a consequence of 20th to 21st century residential build practices

SM Khan, DD Pearson, T Rönnqvist, ME Nielsen… - Scientific Reports, 2021 - nature.com
Radioactive radon gas inhalation is a major cause of lung cancer worldwide and is a
consequence of the built environment. The average radon level of properties built in a given …

[PDF][PDF] Health effects of radon exposure

JK Kang, S Seo, YW Jin - Yonsei medical journal, 2019 - synapse.koreamed.org
Radon is a naturally occurring radioactive material that is formed as the decay product of
uranium and thorium, and is estimated to contribute to approximately half of the average …

[HTML][HTML] Housing risk factors associated with respiratory disease: a systematic review

NN Wimalasena, A Chang-Richards, KIK Wang… - International journal of …, 2021 - mdpi.com
Cold, damp and mouldy housing arises from the degradation of the housing stock over time
due to weathering and a lack of maintenance. Living in such houses is associated with many …

[HTML][HTML] Lung cancer risk in never-smokers: An overview of environmental and genetic factors

ES Cheng, M Weber, J Steinberg… - Chinese Journal of …, 2021 - ncbi.nlm.nih.gov
Lung cancer is the leading cause of cancer-related mortality globally, accounting for 1.8
million deaths in 2020. While the vast majority are caused by tobacco smoking, 15%− 25 …

Lung cancer risk and residential radon exposure: A pooling of case-control studies in northwestern Spain

M Lorenzo-Gonzalez, A Ruano-Ravina… - Environmental …, 2020 - Elsevier
Background Through a pooled case-control study design, we have assessed the
relationship between residential radon exposure and lung cancer risk. Other objectives of …