[HTML][HTML] Natural small molecules in breast cancer treatment: understandings from a therapeutic viewpoint

MR Islam, F Islam, MH Nafady, M Akter, S Mitra, R Das… - Molecules, 2022 - mdpi.com
Breast cancer (BrCa) is the most common malignancy in women and the second most
significant cause of death from cancer. BrCa is one of the most challenging malignancies to …

Honokiol for cancer therapeutics: A traditional medicine that can modulate multiple oncogenic targets

K Banik, AM Ranaware, V Deshpande… - Pharmacological …, 2019 - Elsevier
In spite of billions of dollars expended on cancer research every year, the incidence rate and
the mortality rate due to this widespread disease has increased drastically over the last few …

Mitigation of honokiol on fluoride-induced mitochondrial oxidative stress, mitochondrial dysfunction, and cognitive deficits through activating AMPK/PGC-1α/Sirt3

D Wang, L Cao, X Zhou, G Wang, Y Ma, X Hao… - Journal of hazardous …, 2022 - Elsevier
Oxidative stress and mitochondrial dysfunction contribute greatly to fluoride-induced
cognitive impairment and behavioural disorders. Honokiol, a natural biphenolic compound …

[HTML][HTML] Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

VB Pillai, S Samant, NR Sundaresan… - Nature …, 2015 - nature.com
Honokiol (HKL) is a natural biphenolic compound derived from the bark of magnolia trees
with anti-inflammatory, anti-oxidative, anti-tumour and neuroprotective properties. Here we …

The emerging role of paraptosis in tumor cell biology: Perspectives for cancer prevention and therapy with natural compounds

F Fontana, M Raimondi, M Marzagalli… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Standard anti-cancer therapies promote tumor growth suppression mainly via induction of
apoptosis. However, in most cases cancer cells acquire the ability to escape apoptotic cell …

[HTML][HTML] Herbal drugs and natural bioactive products as potential therapeutics: A review on pro-cognitives and brain boosters perspectives

S Halder, U Anand, S Nandy, P Oleksak, S Qusti… - Saudi Pharmaceutical …, 2021 - Elsevier
Memory, one of the most vital aspects of the human brain, is necessary for the effective
survival of an individual.'Memory'can be defined in various ways but in an overall view …

[HTML][HTML] Honokiol: a review of its anticancer potential and mechanisms

CP Ong, WL Lee, YQ Tang, WH Yap - Cancers, 2019 - mdpi.com
Cancer is characterised by uncontrolled cell division and abnormal cell growth, which is
largely caused by a variety of gene mutations. There are continuous efforts being made to …

[HTML][HTML] Pharmacology, toxicity, bioavailability, and formulation of magnolol: An update

Y Lin, Y Li, Y Zeng, B Tian, X Qu, Q Yuan… - Frontiers in …, 2021 - frontiersin.org
Magnolol (MG) is one of the primary active components of Magnoliae officinalis cortex,
which has been widely used in traditional Chinese and Japanese herbal medicine and …

[HTML][HTML] Sirt3 ameliorates oxidative stress and mitochondrial dysfunction after intracerebral hemorrhage in diabetic rats

J Zheng, L Shi, F Liang, W Xu, T Li, L Gao… - Frontiers in …, 2018 - frontiersin.org
Aim: Sirtuin3 (sirt3) plays a pivotal role in improving oxidative stress and mitochondrial
dysfunction which directly induced neuronal apoptosis after intracerebral hemorrhage (ICH) …

[HTML][HTML] Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice

VB Pillai, A Kanwal, YH Fang, WW Sharp, S Samant… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Doxorubicin is the chemotherapeutic drug of choice for a wide variety of cancers, and
cardiotoxicity is one of the major side effects of doxorubicin treatment. One of the main …