Animal models of asthma: utility and limitations
MV Aun, R Bonamichi-Santos… - Journal of asthma …, 2017 - Taylor & Francis
Clinical studies in asthma are not able to clear up all aspects of disease pathophysiology.
Animal models have been developed to better understand these mechanisms and to …
Animal models have been developed to better understand these mechanisms and to …
Heaves, an asthma‐like disease of horses
M Leclere, A LAVOIE‐LAMOUREUX, JP LAVOIE - Respirology, 2011 - Wiley Online Library
Animal models have been developed to investigate specific components of asthmatic airway
inflammation, hyper‐responsiveness or remodelling. However, all of these aspects are …
inflammation, hyper‐responsiveness or remodelling. However, all of these aspects are …
Equine asthma: Integrative biologic relevance of a recently proposed nomenclature
The term “equine asthma” has been proposed as a unifying descriptor of inflammatory
airway disease (IAD), recurrent airway obstruction (RAO), and summer pasture‐associated …
airway disease (IAD), recurrent airway obstruction (RAO), and summer pasture‐associated …
Asthma “of horses and men”—How can equine heaves help us better understand human asthma immunopathology and its functional consequences?
Animal models have been studied to unravel etiological, immunopathological, and genetic
attributes leading to asthma. However, while experiments in which the disease is artificially …
attributes leading to asthma. However, while experiments in which the disease is artificially …
Pathological roles of neutrophil‐mediated inflammation in asthma and its potential for therapy as a target
H Gao, S Ying, Y Dai - Journal of immunology research, 2017 - Wiley Online Library
Asthma is a chronic inflammatory disease that undermines the airways. It is caused by
dysfunction of various types of cells, as well as cellular components, and is characterized by …
dysfunction of various types of cells, as well as cellular components, and is characterized by …
Recurrent airway obstruction: a review
RS Pirie - Equine veterinary journal, 2014 - Wiley Online Library
Recurrent airway obstruction is a widely recognised airway disorder, characterised by
hypersensitivity‐mediated neutrophilic airway inflammation and lower airway obstruction in …
hypersensitivity‐mediated neutrophilic airway inflammation and lower airway obstruction in …
Effect of Syringic acid on antioxidant biomarkers and associated inflammatory markers in mice model of asthma
Y Li, L Zhang, X Wang, W Wu… - Drug Development …, 2019 - Wiley Online Library
Asthma is termed as the induction of chronic inflammation in the airway lumen of lungs due
to accumulation of inflammatory cells which affects normal breathing process. Prolonged …
to accumulation of inflammatory cells which affects normal breathing process. Prolonged …
The role of interleukin‐4 in rheumatic diseases
C Dong, T Fu, J Ji, Z Li, Z Gu - Clinical and experimental …, 2018 - Wiley Online Library
Rheumatism is a group of diseases, most of which are autoimmune diseases, that violate
joints, bones, muscles, blood vessels and related soft tissue. As is well known, cytokines …
joints, bones, muscles, blood vessels and related soft tissue. As is well known, cytokines …
Rapid and label-free microfluidic neutrophil purification and phenotyping in diabetes mellitus
Advanced management of dysmetabolic syndromes such as diabetes will benefit from a
timely mechanistic insight enabling personalized medicine approaches. Herein, we present …
timely mechanistic insight enabling personalized medicine approaches. Herein, we present …
Markers of systemic inflammation in horses with heaves
A Lavoie‐Lamoureux, M Leclere… - Journal of veterinary …, 2012 - Wiley Online Library
Background Systemic inflammation in horses with heaves is poorly characterized.
Objectives To assess acute phase proteins (APP) and inflammatory cytokine profiles in …
Objectives To assess acute phase proteins (APP) and inflammatory cytokine profiles in …