Targeting ferroptosis in acute kidney injury

L Ni, C Yuan, X Wu - Cell Death & Disease, 2022 - nature.com
Acute kidney injury (AKI) is a major public health problem with high incidence and mortality.
As a form of programmed cell death (PCD), ferroptosis could be considered as a process of …

Ferroptosis and its emerging roles in cardiovascular diseases

N Li, W Jiang, W Wang, R Xiong, X Wu… - Pharmacological Research, 2021 - Elsevier
Ferroptosis is a new form of regulated cell death (RCD) driven by iron-dependent lipid
peroxidation, which is morphologically and mechanistically distinct from other forms of RCD …

Ferroptosis: a new regulatory mechanism in osteoporosis

P Liu, W Wang, Z Li, Y Li, X Yu, J Tu… - Oxidative Medicine and …, 2022 - Wiley Online Library
Osteoporosis can be caused by a multitude of factors and is defined by a decrease in bone
density and mass caused by the destruction of bone microstructure, resulting in increased …

Role of ferroptosis in stroke

Y Xu, K Li, Y Zhao, L Zhou, Y Liu, J Zhao - Cellular and Molecular …, 2023 - Springer
Stroke is a common and serious nervous system disease caused by the rupture or blockage
of the cardiovascular system. It causes millions of deaths and disabilities every year, which …

Novel targets, treatments, and advanced models for intracerebral haemorrhage

M Zille, TD Farr, RF Keep, C Römer, G Xi, J Boltze - EBioMedicine, 2022 - thelancet.com
Intracerebral haemorrhage (ICH) is the second most common type of stroke and a major
cause of mortality and disability worldwide. Despite advances in surgical interventions and …

Curcumin nanoparticles inhibiting ferroptosis for the enhanced treatment of intracerebral hemorrhage

C Yang, M Han, R Li, L Zhou, Y Zhang… - International Journal …, 2021 - Taylor & Francis
Background Intracerebral hemorrhage (ICH) is a form of severe stroke, the pathology of
which is tied closely to a recently discovered form of programmed cell death known as …

Nanoparticles in the diagnosis and treatment of vascular aging and related diseases

H Xu, S Li, YS Liu - Signal Transduction and Targeted Therapy, 2022 - nature.com
Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …

Microwave assisted extraction, characterization of a polysaccharide from Salvia miltiorrhiza Bunge and its antioxidant effects via ferroptosis-mediated activation of the …

H Meng, J Wu, L Shen, G Chen, L Jin, M Yan… - International Journal of …, 2022 - Elsevier
A microwave-assisted extraction procedure for the crude Salvia miltiorrhiza polysaccharides
(SMPs) obtained from Salvia miltiorrhiza Bunge was optimized. Four independent variables …

Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases

Y Wang, J Hu, S Wu, JS Fleishman, Y Li, Y Xu… - … and Targeted Therapy, 2023 - nature.com
Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …

[HTML][HTML] Ferroptosis and musculoskeletal diseases:“Iron Maiden” cell death may be a promising therapeutic target

Y Zhang, X Huang, B Qi, C Sun, K Sun, N Liu… - Frontiers in …, 2022 - frontiersin.org
Ferroptosis is a novel form of cell death precisely regulated by iron metabolism, antioxidant
processes, and lipid metabolism that plays an irreplaceable role in the development of many …