Carbon–Carbon Bond Cleavage for Late-Stage Functionalization

YF Liang, M Bilal, LY Tang, TZ Wang, YQ Guan… - Chemical …, 2023 - ACS Publications
Late-stage functionalization (LSF) introduces functional group or structural modification at
the final stage of the synthesis of natural products, drugs, and complex compounds. It is …

Photoexcited nitroarenes for the oxidative cleavage of alkenes

A Ruffoni, C Hampton, M Simonetti, D Leonori - Nature, 2022 - nature.com
The oxidative cleavage of alkenes is an integral process that converts feedstock materials
into high-value synthetic intermediates,–. The most viable method to achieve this in one …

Nitrogen dioxide catalyzed aerobic oxidative cleavage of C (OH)–C bonds of secondary alcohols to produce acids

M Liu, Z Zhang, J Song, S Liu, H Liu… - Angewandte …, 2019 - Wiley Online Library
Stable organic nitroxyl radicals are an important class of catalysts for oxidation reactions, but
their wide applications are hindered by their steric hinderance, high cost, complex operation …

Selective oxidation of alkenes to carbonyls under mild conditions

J Xu, Y Zhang, X Yue, J Huo, D Xiong, P Zhang - Green Chemistry, 2021 - pubs.rsc.org
Herein, a practical and sustainable method for the synthesis of aldehydes, ketones, and
carboxylic acids from an inexpensive olefinic feedstock is described. This transformation …

Oxidative Cleavage of Alkenes by O2 with a Non-Heme Manganese Catalyst

Z Huang, R Guan, M Shanmugam… - Journal of the …, 2021 - ACS Publications
The oxidative cleavage of C═ C double bonds with molecular oxygen to produce carbonyl
compounds is an important transformation in chemical and pharmaceutical synthesis. In …

Photochemical organocatalytic aerobic cleavage of C═ C bonds enabled by charge-transfer complex formation

YX Chen, JT He, MC Wu, ZL Liu, K Tang, PJ Xia… - Organic …, 2022 - ACS Publications
A novel visible-light-driven organocatalytic protocol to access aerobic oxidative cleavage of
olefins, promoted by sodium benzene sulfinate, is described herein. An array of alkenes …

Bis (methoxypropyl) ether-promoted oxidation of aromatic alcohols into aromatic carboxylic acids and aromatic ketones with O 2 under metal-and base-free conditions

KJ Liu, S Jiang, LH Lu, LL Tang, SS Tang, HS Tang… - Green …, 2018 - pubs.rsc.org
We describe an eco-friendly, practical and operationally simple procedure for the bis
(methoxypropyl) ether-promoted oxidation of aromatic alcohols into aromatic carboxylic …

Switchable Synthesis of Aryl Sulfones and Sulfoxides through Solvent-Promoted Oxidation of Sulfides with O2/Air

Z Cheng, P Sun, A Tang, W Jin, C Liu - Organic letters, 2019 - ACS Publications
A practical and switchable method for the synthesis of aryl sulfones and sulfoxides via
sulfide oxidation was developed. The chemoselectivities of products were simply controlled …

Scalable electrochemical aerobic oxygenation of indoles to isatins without electron transfer mediators by merging with an oxygen reduction reaction

W Zhuang, J Zhang, C Ma, JS Wright, X Zhang… - Organic …, 2022 - ACS Publications
An approach to electrochemical oxygenation of indoles leading to isatins was developed by
merging with a complementary cathode oxygen reduction reaction. The features of this …

Photocatalytic carboxylation of styrenes with CO2 via C= C double bond cleavage

KG Cao, TY Gao, LL Liao, CK Ran, YX Jiang… - Chinese Journal of …, 2024 - Elsevier
Catalytic cleavage of C= C double bonds in alkenes is highly important to convert feedstocks
into high-value compounds. However, these approaches are mainly limited to oxidative …