Background Direct-acting oral anticoagulants (DOACs) are increasingly used, with studies
showing a lower risk of gastrointestinal bleeding (GIB), but overall data for GIB risk remains …

Nonvalvular atrial fibrillation (NVAF) is associated with an increased risk of stroke and
thrombus, and anticoagulant therapy is a key link in the prevention of stroke. At present, the …

Aims This study aimed to evaluate the prescriber compliance to the approved labels of direct
oral anticoagulants (DOACs) and impact of appropriateness of dosing on clinical outcomes …

Although low-dose direct oral anticoagulants (DOACs) are recommended for patients at high
risk of bleeding complications, it remains unclear whether the dose reduction in real-world …

The new generation of nonvitamin K antagonists are broadly applied for stroke prevention
due to their notable efficacy and safety. Our study aimed to develop a suggestive utilization …

Patients with atrial fibrillation (AF) commonly have associated comorbidities. The primary
aim was to determine the effect of increasing numbers of comorbidity on clinical outcomes …

We aimed to compare the ability to balance baseline covariates and explore the impact of
residual confounding between conventional and machine learning approaches to derive …

Background To clarify the appropriate initial dosage of heparin during radiofrequency
catheter ablation (RFCA) in patients with atrial fibrillation (AF) receiving uninterrupted …

Abstract Background/Introduction Previous observational studies reported that off-label
underdosed apixaban might be associated with a higher risk of stroke. However, the real …

Backgrounds Non-vitamin K antagonist oral anticoagulants (NOACs) have been
recommended as the first choice over warfarin for non-valvular atrial fibrillation (AF) …