Purpose Oxygen therapy is vital in adult intensive care unit (ICU) patients, but it is indistinct
whether higher or lower oxygen targets are favorable. Our aim was to update the findings of …

Background: Oxygen is the commonest intervention provided to critically ill patients requiring
mechanical ventilation. Despite this, it is unclear how much oxygen should be administered …

Virtually, every drug has an effective and toxic dose and oxygen is no exception. Molecular
oxygen has been referred to as “janus-headed”, inasmuch as it is vital for mitochondrial …

Background: In the United Kingdom, around 184,000 adults are admitted to an intensive
care unit (ICU) each year with over 30% receiving mechanical ventilation. Oxygen is the …

The present study aimed to assess the effect of a conservative (permissive hypoxemia)
versus conventional (normoxia) protocol for oxygen supplementation on the outcome of type …

Background It remains unclear whether conservative oxygen therapy (COT) or liberal
oxygen therapy (LOT) is more beneficial to the clinical outcomes of intensive care unit (ICU) …

Background Oxygen therapy (OT) is a commonly prescribed essential medicine for people of
all ages in the management of hypoxia. The adverse effects of inappropriate OT …

In a recent paper, Chen et al. report the findings of a systematic review with meta-analysis
concerning conservative versus conventional oxygen therapy for critically ill patients. We …

Supplemental oxygen is a standard therapeutic intervention for critically ill patients such as
patients suffering from cardiac arrest, myocardial ischemia, traumatic brain injury, and …

Higher versus lower oxygenation strategies in the general intensive care unit population: A
systematic review, meta-analysis and meta-regression of randomized controlled trials Page 62 …