Somatic mutations occur spontaneously in normal individuals and accumulate throughout
life. These genetic modifications contribute to progressive ageing phenotypes and are …

Peripheral blood stem cells (PBSCs) have become increasingly popular for use in
hematopoietic stem cell transplantation. PBSCs are readily collected by continuous-flow …

Allogeneic hematopoietic cell transplantation (allo-HCT) is potentially curative for certain
hematologic malignancies and nonmalignant diseases. The field of allo-HCT has witnessed …

Hematopoietic progenitor cells (HPCs) traffic to and are retained in the marrow through the
trophic effects of the chemokine stromal cell-derived factor-1α (SDF-1α) binding to its …

We report here the transplantation of extensively purified" mobilized" peripheral blood
CD34Thy-1 hematopoietic stem cells from 22 patients with recurrent or metastatic breast …

Hematopoietic stem cells can be collected from the peripheral blood. These hematopoietic
stem cells (HSC), or better progenitor cells, are mostly expressed as the percentage of cells …

High-risk neuroblastoma is a childhood malignancy with a poor prognosis. Gradual
improvements in survival have correlated with therapeutic intensity, and the ability to …

High-dose cyclophosphamide (HDC) has been shown to be an effective regimen for
collecting PBPC in multiple myeloma (MM) patients, but the optimal dose to be used remains …

The BMT program at Princess Margaret Hospital performed 105 transplants using
cryopreserved peripheral blood stem cells (PBSC) from related allogeneic donors. The …

Delayed immune reconstitution in adult recipients of allogeneic hemopoietic stem cell
transplantations (HSCT) is related to age-induced thymic atrophy. Overcoming this paucity of …