A brief overview is provided of cosinor-based techniques for the analysis of time series in
chronobiology. Conceived as a regression problem, the method is applicable to non …

Circadian rhythms are ubiquitous phenomena that recur daily in a self-sustaining,
entrainable, and oscillatory manner, and orchestrate a wide range of molecular …

Time-restricted feeding (TRF) improves metabolic health. Both early TRF (eTRF, food intake
restricted to the early part of the day) and mid-day TRF (mTRF, food intake restricted to the …

Sleep is integral to life. Although insufficient or disrupted sleep increases the risk of multiple
pathological conditions, including cardiovascular disease, we know little about the cellular …

Microbiota-derived short-chain fatty acids (SCFAs) and organic acids produced by the
fermentation of non-digestible fibre can communicate from the microbiome to host tissues …

Group 3 innate lymphoid cells (ILC3s) are major regulators of inflammation, infection,
microbiota composition and metabolism. ILC3s and neuronal cells have been shown to …

Motivation A fundamental interest in chronobiology is to compare patterns between groups
of rhythmic data. However, many existing methods are ill-equipped to derive statements …

Circadian rhythms modulate many aspects of physiology. Knowledge of the molecular basis
of these rhythms has exploded in the last 20 years. However, most of these data are from …

One of the primary outputs of the scientific enterprise is data, but many institutions such as
libraries that are charged with preserving and disseminating scholarly output have largely …

Healthy individuals exhibit blood pressure variation over a 24-hour period with higher blood
pressure during wakefulness and lower blood pressure during sleep. Loss or disruption of …