[HTML][HTML] Plant-derived anticancer agents: A green anticancer approach

J Iqbal, BA Abbasi, T Mahmood, S Kanwal, B Ali… - Asian Pacific Journal of …, 2017 - Elsevier
Cancer is a frightful disease and represents one of the biggest health-care issues for the
human race and demands a proactive strategy for cure. Plants are reservoirs for novel …

The Pharmacological Activities of Crocus sativus L.: A Review Based on the Mechanisms and Therapeutic Opportunities of its Phytoconstituents

M Butnariu, C Quispe, J Herrera-Bravo… - Oxidative medicine …, 2022 - Wiley Online Library
Crocus species are mainly distributed in North Africa, Southern and Central Europe, and
Western Asia, used in gardens and parks as ornamental plants, while Crocus sativus …

[HTML][HTML] Antioxidant role of kaempferol in prevention of hepatocellular carcinoma

N Sharma, S Biswas, N Al-Dayan, AS Alhegaili… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are noxious to cells because their increased level interacts
with the body's defense mechanism. These species also cause mutations and uncontrolled …

[HTML][HTML] Immunoregulatory and anti-inflammatory properties of Crocus sativus (Saffron) and its main active constituents: A review

M Zeinali, MR Zirak, SA Rezaee, G Karimi… - Iranian Journal of …, 2019 - ncbi.nlm.nih.gov
The medicinal uses of saffron, the dried stigmas of Crocus sativus L., have very long history
in food coloring agent, and flavoring agent as well as traditional medicine for the treatment of …

[HTML][HTML] The role of Safranal and saffron stigma extracts in oxidative stress, diseases and photoaging: A systematic review

S Nanda, K Madan - Heliyon, 2021 - cell.com
Reactive oxygen species (ROS) are produced as a result of various environmental factors
and cellular metabolism reactions creating oxidative stress. The reversible oxidative …

Biologically active compounds and pharmacological activities of species of the genus Crocus: A review

O Mykhailenko, V Kovalyov, O Goryacha, L Ivanauskas… - Phytochemistry, 2019 - Elsevier
The present article is the first comprehensive review on the chemical composition and
pharmacological activities of the raw materials of Crocus species. In the present review, data …

Are polyphenol antioxidants at the root of medicinal plant anti-cancer success?

AB Oyenihi, C Smith - Journal of ethnopharmacology, 2019 - Elsevier
Ethnopharmacological relevance Given the severe side effects associated with most of the
conventional cancer medications, as well as the expanding body of evidence indicating …

[HTML][HTML] Safranal Inhibits Angiogenesis via Targeting HIF-1α/VEGF Machinery: In Vitro and Ex Vivo Insights

A Abdalla, C Murali, A Amin - Frontiers in Oncology, 2022 - frontiersin.org
Nature has a nearly infinite inventory of unexplored phytochemicals and biomolecules that
have the potential to treat a variety of diseases. Safranal exhibits anti-cancer property and …

Apocarotenoids: emerging roles in mammals

EH Harrison, L Quadro - Annual review of nutrition, 2018 - annualreviews.org
Apocarotenoids are cleavage products of C40 isoprenoid pigments, named carotenoids,
synthesized exclusively by plants and microorganisms. The colors of flowers and fruits and …

[HTML][HTML] Pharmacological effects of Safranal: An updated review

D Esmaealzadeh, AAM Ghalibaf, MS Rad… - Iranian journal of …, 2023 - ncbi.nlm.nih.gov
Safranal (a monoterpene aldehyde) is the major volatile component of saffron which is
responsible for the saffron unique odor. Several studies have shown the pharmacological …