Periodontal disease: a risk factor for diabetes and cardiovascular disease

D Liccardo, A Cannavo, G Spagnuolo… - International journal of …, 2019 - mdpi.com
Periodontitis is a chronic inflammatory disease, initiated by the presence of a bacterial
biofilm, called dental plaque, which affects both the periodontal ligaments and bone …

Chronic periodontitis, inflammatory cytokines, and interrelationship with other chronic diseases

EM Cardoso, C Reis… - Postgraduate …, 2018 - Taylor & Francis
Periodontal diseases, such as chronic periodontitis, share common inflammatory risk factors
with other systemic and chronic inflammatory disorders. Mucosal tissues, such as oral …

Periodontal disease and atherosclerotic vascular disease: does the evidence support an independent association? A scientific statement from the American Heart …

PB Lockhart, AF Bolger, PN Papapanou… - Circulation, 2012 - Am Heart Assoc
A link between oral health and cardiovascular disease has been proposed for more than a
century. Recently, concern about possible links between periodontal disease (PD) and …

A systematic review and meta‐analyses on C‐reactive protein in relation to periodontitis

S Paraskevas, JD Huizinga… - Journal of clinical …, 2008 - Wiley Online Library
Aim: Elevated plasma C‐reactive protein (CRP) is regarded as a risk predictor for
cardiovascular diseases. This systematic review explored the robustness of observations …

Gum Bug, Leave My Heart Alone!”—Epidemiologic and Mechanistic Evidence Linking Periodontal Infections and Atherosclerosis

M Kebschull, RT Demmer… - Journal of dental …, 2010 - journals.sagepub.com
Evidence from epidemiologic studies suggests that periodontal infections are independently
associated with subclinical and clinical atherosclerotic vascular disease. Although the …

Infection and inflammatory mechanisms

TE Van Dyke, AJ Van Winkelhoff - Journal of clinical …, 2013 - Wiley Online Library
This introductory article examines the potential mechanisms that may play a role in the
associations between periodontitis and the systemic conditions being considered in the …

Evidence that periodontal treatment improves biomarkers and CVD outcomes

F D'Aiuto, M Orlandi, JC Gunsolley - Journal of periodontology, 2013 - Wiley Online Library
Aim: The aim of this review was to critically appraise the evidence on the impact of
periodontal treatment of cardiovascular diseases (CVDs) biomarkers and outcomes …

[HTML][HTML] Inflammation in periodontal disease: possible link to vascular disease

O Paul, P Arora, M Mayer, S Chatterjee - Frontiers in Physiology, 2021 - frontiersin.org
Inflammation is a well-organized protective response to pathogens and consists of immune
cell recruitment into areas of infection. Inflammation either clears pathogens and gets …

Periodontal disease and systemic illness: will the evidence ever be enough?

MP Cullinan, GJ Seymour - Periodontology 2000, 2013 - Wiley Online Library
The concept of focal infection or systemic disease arising from infection of the teeth was
generally accepted until the mid‐20th century when it was dismissed because of lack of …

Low‐grade inflammation in chronic infectious diseases: paradigm of periodontal infections

NM Moutsopoulos, PN Madianos - … of the New York Academy of …, 2006 - Wiley Online Library
Increasing evidence implicates periodontitis, a chronic inflammatory disease of the tooth‐
supporting structures, as a potential risk factor for increased morbidity or mortality for several …