Regulator of G Protein Signaling 6 Facilities Cardiac Hypertrophy by Activating Apoptosis Signal–Regulating Kinase 1–P38/c‐JUN N‐Terminal Kinase 1/2 Signaling

Z Huang, J Shu, W Jiang, M Jiang, Y Lu… - Journal of the …, 2018 - Am Heart Assoc
Background Regulator of G protein signaling 6 (RGS 6) is an important member of the RGS
family and produces pleiotropic regulatory effects on cardiac pathophysiology. However, the …

[HTML][HTML] Repeated exposure to methamphetamine induces sex-dependent hypersensitivity to ischemic injury in the adult rat heart

BR Rorabaugh, SL Seeley, TS Stoops, MS D'Souza - PloS one, 2017 - journals.plos.org
Background We previously reported that adult female, but not male rats that were prenatally
exposed to methamphetamine exhibit myocardial hypersensitivity to ischemic injury …

[HTML][HTML] The influences of the M2R-GIRK4-RGS6 dependent parasympathetic pathway on electrophysiological properties of the mouse heart

K Kulkarni, X Xie, EM Fernandez de Velasco… - PloS one, 2018 - journals.plos.org
A large body of work has established the prominent roles of the atrial M2R-IKACh signaling
pathway, and the negative regulatory protein RGS6, in modulating critical aspects of …

Myocardial hypersensitivity to ischemic injury is not reversed by clonidine or propranolol in a predator-based rat model of posttraumatic stress disorder

BR Rorabaugh, AD Bui, SL Seeley… - Progress in Neuro …, 2019 - Elsevier
Individuals with posttraumatic stress disorder (PTSD) are at increased risk for cardiovascular
disease. We previously reported that a predator-based model of PTSD increases myocardial …

Regulators of G protein Signaling (RGS) proteins in GtoPdb v. 2021.2

KE Ahlers-Dannen, M Alqinyah, C Bodle… - IUPHAR/BPS Guide …, 2021 - journals.ed.ac.uk
Regulator of G protein Signaling, or RGS, proteins serve an important regulatory role in
signaling mediated by G protein-coupled receptors (GPCRs). They all share a common RGS …

RGS17 在冠状动脉粥样硬化中的表达.

熊鑫, 杨启琨, 刘凯, 瞿勇强, 雷普平… - Journal of Kunming …, 2020 - search.ebscohost.com
目的通过免疫组织化学染色来验证RGS17 在人冠心病猝死者冠状动脉管壁组织中的表达情况.
方法收集冠心病猝死案例41 例(实验组) 及非心源性死亡10 例(对照组), 根据冠脉狭窄程度分为 …

[HTML][HTML] Short term methylphenidate treatment does not increase myocardial injury in the ischemic rat heart

SL Seeley, MS D'SOUZA, TS Stoops… - Physiological …, 2020 - ncbi.nlm.nih.gov
Methylphenidate is commonly used for the treatment of attention deficit hyperactivity
disorder. The cardiovascular safety of methylphenidate has been a subject of debate with …

Modulating Cardiac Dynamics: The Prediction, Prevention and Control of Cardiac Alternans

K Kulkarni - 2017 - search.proquest.com
The human heart is a fascinating machine whose mechanical and electrical synergy creates
a powerful and efficient dynamic system that beats tirelessly over two billion times in an …

Regulators of G protein Signaling (RGS) proteins (version 2020.5) in the IUPHAR/BPS Guide to Pharmacology Database

KE Ahlers-Dannen, M Alqinyah, C Bodle… - IUPHAR/BPS Guide …, 2020 - journals.ed.ac.uk
Regulators of G protein Signaling (RGS) proteins (version 2020.5) in the IUPHAR/BPS
Guide to Pharmacology Database Page 1 IUPHAR/BPS Guide to Pharmacology CITE https://doi.org/10.2218/gtopdb/F891/2020.5 …

The Role of Regulator of G Protein Signaling 2 in Inflammatory Cytokine Release in Endotoxemia in Mice

XT Ma - 2020 - search.proquest.com
In sepsis, lipopolysaccharide (LPS) activates toll-like receptor 4 to stimulate the release of
inflammatory cytokines (eg tumor necrosis factor-alpha, TNF-α), leading to cardiac …