Acinetobacter are a major concern because of their rapid development of resistance to a
wide range of antimicrobials, and rapid profundity in transformation, surviving desiccation …

In 1959, Arthur Kornberg was awarded the Nobel Prize for his work on the principles by
which DNA is duplicated by DNA polymerases. Since then, it has been confirmed in all …

Antimicrobial resistance has emerged as a global threat to human health. Natural
transformation is an important pathway for horizontal gene transfer, which facilitates the …

Bacterial genomics has greatly expanded our understanding of microdiversification patterns
within a species, but analyses at higher taxonomical levels are necessary to understand and …

Toxin-antitoxin (TA) systems are ubiquitous on bacterial chromosomes, yet the mechanisms
regulating their activity and the molecular targets of toxins remain incompletely defined …

A unique, protective cell envelope contributes to the broad drug resistance of the
nosocomial pathogen Acinetobacter baumannii. Here we use transposon insertion …

Rates of infection with hospital-acquired Acinetobacter baumannii have exploded over the
past decade due to our inability to limit persistence and effectively treat disease. A …

The nosocomial pathogen Acinetobacter baumannii is a significant threat due to its ability to
cause infections refractory to a broad range of antibiotic treatments. We show here that a …

RecA is the major enzyme involved in homologous recombination and plays a central role in
SOS mutagenesis. In Acinetobacter spp., including Acinetobacter baumannii, a multidrug …

Bacterial transformation is a programmed process resulting in genetic transfer and diversity.
It relies on the development of competence via regulatory circuits which are diverse and …