[HTML][HTML] Role of sleep deprivation in immune-related disease risk and outcomes

S Garbarino, P Lanteri, NL Bragazzi… - Communications …, 2021 - nature.com
Modern societies are experiencing an increasing trend of reduced sleep duration, with
nocturnal sleeping time below the recommended ranges for health. Epidemiological and …

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

H Sies, DP Jones - Nature reviews Molecular cell biology, 2020 - nature.com
Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …

Circadian rhythms in neurodegenerative disorders

M Nassan, A Videnovic - Nature Reviews Neurology, 2022 - nature.com
Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …

[HTML][HTML] Dietary regulation in health and disease

Q Wu, ZJ Gao, X Yu, P Wang - Signal Transduction and Targeted …, 2022 - nature.com
Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

Clocks, cancer, and chronochemotherapy

A Sancar, RN Van Gelder - Science, 2021 - science.org
BACKGROUND The core of the mammalian circadian clock mechanism is a time-delayed
transcription-translation feedback loop (TTFL), which influences the transcription and …

Circadian mechanisms in medicine

R Allada, J Bass - New England Journal of Medicine, 2021 - Mass Medical Soc
Circadian Mechanisms in Medicine Molecular insights into diurnal variations in human
physiology and behavior are extending our understanding of a wide range of disease …

Magnetic field effects in biology from the perspective of the radical pair mechanism

H Zadeh-Haghighi, C Simon - Journal of the Royal …, 2022 - royalsocietypublishing.org
Hundreds of studies have found that weak magnetic fields can significantly influence various
biological systems. However, the underlying mechanisms behind these phenomena remain …

A photoregulatory mechanism of the circadian clock in Arabidopsis

X Wang, B Jiang, L Gu, Y Chen, M Mora, M Zhu… - Nature plants, 2021 - nature.com
Cryptochromes (CRYs) are photoreceptors that mediate light regulation of the circadian
clock in plants and animals. Here we show that CRYs mediate blue-light regulation of N6 …

[HTML][HTML] The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock

JF Brooks, CL Behrendt, KA Ruhn, S Lee, P Raj… - Cell, 2021 - cell.com
Environmental light cycles entrain circadian feeding behaviors in animals that produce
rhythms in exposure to foodborne bacteria. Here, we show that the intestinal microbiota …

[HTML][HTML] Roles of circadian clocks in cancer pathogenesis and treatment

Y Lee - Experimental & molecular medicine, 2021 - nature.com
Circadian clocks are ubiquitous timing mechanisms that generate approximately 24-h
rhythms in cellular and bodily functions across nearly all living species. These internal clock …