[HTML][HTML] Blood–brain barrier dynamics to maintain brain homeostasis
M Segarra, MR Aburto, A Acker-Palmer - Trends in neurosciences, 2021 - cell.com
The blood–brain barrier (BBB) is a dynamic platform for exchange of substances between
the blood and the brain parenchyma, and it is an essential functional gatekeeper for the …
the blood and the brain parenchyma, and it is an essential functional gatekeeper for the …
Molecular mechanisms of high-altitude acclimatization
RT Mallet, J Burtscher, V Pialoux, Q Pasha… - International journal of …, 2023 - mdpi.com
High-altitude illnesses (HAIs) result from acute exposure to high altitude/hypoxia. Numerous
molecular mechanisms affect appropriate acclimatization to hypobaric and/or normobaric …
molecular mechanisms affect appropriate acclimatization to hypobaric and/or normobaric …
Rhodiola crenulate alleviates hypobaric hypoxia-induced brain injury via adjusting NF-κB/NLRP3-mediated inflammation
N Xie, F Fan, S Jiang, Y Hou, Y Zhang, N Cairang… - Phytomedicine, 2022 - Elsevier
Background Rhodiola crenulate (R. crenulate), a famous Tibetan medicine, has been
demonstrated to possess superiorly protective effects in high-altitude hypoxic brain injury …
demonstrated to possess superiorly protective effects in high-altitude hypoxic brain injury …
High-altitude cerebral edema: its own entity or end-stage acute mountain sickness?
REF Turner, H Gatterer, M Falla… - Journal of Applied …, 2021 - journals.physiology.org
High-altitude cerebral edema (HACE) and acute mountain sickness (AMS) are
neuropathologies associated with rapid exposure to hypoxia. However, speculation remains …
neuropathologies associated with rapid exposure to hypoxia. However, speculation remains …
Rhodiola crenulata attenuates apoptosis and mitochondrial energy metabolism disorder in rats with hypobaric hypoxia-induced brain injury by regulating the HIF-1α …
X Wang, Y Hou, Q Li, X Li, W Wang, X Ai… - Journal of …, 2019 - Elsevier
Ethnopharmacological relevance Rhodiola crenulata, a traditional Tibetan medicine, has
shown promise in the treatment of hypobaric hypoxia (HH)-induced brain injury. However …
shown promise in the treatment of hypobaric hypoxia (HH)-induced brain injury. However …
Recommendations for women in mountain sports and hypoxia training/conditioning
J Burtscher, A Raberin, F Brocherie, D Malatesta… - Sports Medicine, 2024 - Springer
The (patho-) physiological responses to hypoxia are highly heterogeneous between
individuals. In this review, we focused on the roles of sex differences, which emerge as …
individuals. In this review, we focused on the roles of sex differences, which emerge as …
Salidroside attenuates high altitude hypobaric hypoxia-induced brain injury in mice via inhibiting NF-κB/NLRP3 pathway
S Jiang, F Fan, L Yang, K Chen, Z Sun, Y Zhang… - European Journal of …, 2022 - Elsevier
Salidroside (Sal), an active ingredient from Rhodiola crenulate, has been reported to exert
neuroprotection in cerebral injury from hypobaric hypoxia (HH) at high altitude. However, it …
neuroprotection in cerebral injury from hypobaric hypoxia (HH) at high altitude. However, it …
High altitude hypoxia and oxidative stress: The new hope brought by free radical scavengers
X Li, J Zhang, G Liu, G Wu, R Wang, J Zhang - Life Sciences, 2023 - Elsevier
Various strategies can be employed to prevent and manage altitude illnesses, including
habituation, oxygenation, nutritional support, and medication. Nevertheless, the utilization of …
habituation, oxygenation, nutritional support, and medication. Nevertheless, the utilization of …
[HTML][HTML] High-altitude illnesses: old stories and new insights into the pathophysiology, treatment and prevention
M Burtscher, U Hefti, JP Hefti - Sports Medicine and Health Science, 2021 - Elsevier
Areas at high-altitude, annually attract millions of tourists, skiers, trekkers, and climbers. If not
adequately prepared and not considering certain ascent rules, a considerable proportion of …
adequately prepared and not considering certain ascent rules, a considerable proportion of …
Form and function of the vertebrate and invertebrate blood-brain barriers
AD Dunton, T Göpel, DH Ho, W Burggren - International journal of …, 2021 - mdpi.com
The need to protect neural tissue from toxins or other substances is as old as neural tissue
itself. Early recognition of this need has led to more than a century of investigation of the …
itself. Early recognition of this need has led to more than a century of investigation of the …