Oxidative stress and inflammation in osteoporosis: molecular mechanisms involved and the relationship with microRNAs
T Iantomasi, C Romagnoli, G Palmini, S Donati… - International journal of …, 2023 - mdpi.com
Osteoporosis is characterized by the alteration of bone homeostasis due to an imbalance
between osteoclastic bone resorption and osteoblastic bone formation. Estrogen deficiency …
between osteoclastic bone resorption and osteoblastic bone formation. Estrogen deficiency …
[HTML][HTML] Osteoblast differentiation at a glance
A Rutkovskiy, KO Stensløkken… - Medical science monitor …, 2016 - ncbi.nlm.nih.gov
Ossification is a tightly regulated process, performed by specialized cells called osteoblasts.
Dysregulation of this process may cause inadequate or excessive mineralization of bones or …
Dysregulation of this process may cause inadequate or excessive mineralization of bones or …
Arrhythmogenic cardiomyopathy
D Corrado, C Basso, DP Judge - Circulation research, 2017 - Am Heart Assoc
Arrhythmogenic cardiomyopathy is an inherited heart muscle disorder, predisposing to
sudden cardiac death, particularly in young patients and athletes. Pathological features …
sudden cardiac death, particularly in young patients and athletes. Pathological features …
[HTML][HTML] Multi-omics analysis of human mesenchymal stem cells shows cell aging that alters immunomodulatory activity through the downregulation of PD-L1
Y Gao, Y Chi, Y Chen, W Wang, H Li, W Zheng… - Nature …, 2023 - nature.com
Mesenchymal stem cells (MSCs) possess potent immunomodulatory activity and have been
extensively investigated for their therapeutic potential in treating inflammatory disorders …
extensively investigated for their therapeutic potential in treating inflammatory disorders …
The role of reactive oxygen species in mesenchymal stem cell adipogenic and osteogenic differentiation: a review
Mesenchymal stromal cells (MSCs) are promising candidates for tissue engineering and
regenerative medicine. The multipotent stem cell component of MSC isolates is able to …
regenerative medicine. The multipotent stem cell component of MSC isolates is able to …
Crosstalk between peroxisome proliferator-activated receptor gamma and the canonical WNT/β-catenin pathway in chronic inflammation and oxidative stress during …
A Vallée, Y Lecarpentier - Frontiers in immunology, 2018 - frontiersin.org
Inflammation and oxidative stress are common and co-substantial pathological processes
accompanying, promoting, and even initiating numerous cancers. The canonical WNT/β …
accompanying, promoting, and even initiating numerous cancers. The canonical WNT/β …
Multiple targets of the canonical WNT/β-catenin signaling in cancers
Y Lecarpentier, O Schussler, JL Hébert… - Frontiers in oncology, 2019 - frontiersin.org
Canonical WNT/β-catenin signaling is involved in most of the mechanisms that lead to the
formation and development of cancer cells. It plays a central role in three cyclic processes …
formation and development of cancer cells. It plays a central role in three cyclic processes …
Immunoporosis: immunology of osteoporosis—role of T cells
The role of immune system in various bone pathologies, such as osteoporosis, osteoarthritis,
and rheumatoid arthritis is now well established. This had led to the emergence of a modern …
and rheumatoid arthritis is now well established. This had led to the emergence of a modern …
Forming functional fat: a growing understanding of adipocyte differentiation
AG Cristancho, MA Lazar - Nature reviews Molecular cell biology, 2011 - nature.com
Adipose tissue, which is primarily composed of adipocytes, is crucial for maintaining energy
and metabolic homeostasis. Adipogenesis is thought to occur in two stages: commitment of …
and metabolic homeostasis. Adipogenesis is thought to occur in two stages: commitment of …
Endocrine disrupting chemicals and disease susceptibility
TT Schug, A Janesick, B Blumberg… - The Journal of steroid …, 2011 - Elsevier
Environmental chemicals have significant impacts on biological systems. Chemical
exposures during early stages of development can disrupt normal patterns of development …
exposures during early stages of development can disrupt normal patterns of development …