Osteoporosis is characterized by the alteration of bone homeostasis due to an imbalance
between osteoclastic bone resorption and osteoblastic bone formation. Estrogen deficiency …

Ossification is a tightly regulated process, performed by specialized cells called osteoblasts.
Dysregulation of this process may cause inadequate or excessive mineralization of bones or …

Arrhythmogenic cardiomyopathy is an inherited heart muscle disorder, predisposing to
sudden cardiac death, particularly in young patients and athletes. Pathological features …

Mesenchymal stem cells (MSCs) possess potent immunomodulatory activity and have been
extensively investigated for their therapeutic potential in treating inflammatory disorders …

Mesenchymal stromal cells (MSCs) are promising candidates for tissue engineering and
regenerative medicine. The multipotent stem cell component of MSC isolates is able to …

Inflammation and oxidative stress are common and co-substantial pathological processes
accompanying, promoting, and even initiating numerous cancers. The canonical WNT/β …

Canonical WNT/β-catenin signaling is involved in most of the mechanisms that lead to the
formation and development of cancer cells. It plays a central role in three cyclic processes …

The role of immune system in various bone pathologies, such as osteoporosis, osteoarthritis,
and rheumatoid arthritis is now well established. This had led to the emergence of a modern …

Adipose tissue, which is primarily composed of adipocytes, is crucial for maintaining energy
and metabolic homeostasis. Adipogenesis is thought to occur in two stages: commitment of …

Environmental chemicals have significant impacts on biological systems. Chemical
exposures during early stages of development can disrupt normal patterns of development …