Coronavirus accessory protein ORF3 biology and its contribution to viral behavior and pathogenesis

F Si, S Song, R Yu, Z Li, W Wei, C Wu - Iscience, 2023 - cell.com
Coronavirus porcine epidemic diarrhea virus (PEDV) is classified in the genus
Alphacoronavirus, family Coronaviridae that encodes the only accessory protein, ORF3 …

Small GTPase—A key role in host cell for Coronavirus infection and a potential target for Coronavirus vaccine adjuvant discovery

W Hou, S Wang, H Wu, L Xue, B Wang, S Wang… - Viruses, 2022 - mdpi.com
Small GTPases are signaling molecules in regulating key cellular processes (eg, cell
differentiation, proliferation, and motility) as well as subcellular events (eg, vesicle …

An alphacoronavirus polymerase structure reveals conserved replication factor functions

TK Anderson, PJ Hoferle, KJ Chojnacki… - Nucleic Acids …, 2024 - academic.oup.com
Coronaviruses are a diverse subfamily of viruses containing pathogens of humans and
animals. This subfamily of viruses replicates their RNA genomes using a core polymerase …

Flavonoids as potential antiviral agents for porcine viruses

X Zhang, S Chen, X Li, L Zhang, L Ren - Pharmaceutics, 2022 - mdpi.com
Flavonoids are types of natural substances with phenolic structures isolated from a variety of
plants. Flavonoids have antioxidant, anti-inflammatory, anticancer, and antiviral activities …

Dietary taurine effect on intestinal barrier function, colonic microbiota and metabolites in weanling piglets induced by LPS

D Zhao, Y Gai, C Li, Z Fu, DQ Yin, M Xie, J Dai… - Frontiers in …, 2023 - frontiersin.org
Diarrhea in piglets is one of the most important diseases and a significant cause of death in
piglets. Preliminary studies have confirmed that taurine reduces the rate and index of …

[HTML][HTML] Nutrition strategies to control post-weaning diarrhea of piglets: from the perspective of feeds

Q Tang, T Lan, C Zhou, J Gao, L Wu, H Wei, W Li… - Animal Nutrition, 2024 - Elsevier
Post-weaning diarrhea (PWD) is a globally significant threat to the swine industry.
Historically, antibiotics as well as high doses of zinc oxide and copper sulfate have been …

Activation of the NLRP1 inflammasome and its role in transmissible gastroenteritis coronavirus infection

H He, W Wang, L Li, X Zhang, H Shi, J Chen… - Journal of …, 2023 - Am Soc Microbiol
The inflammasome pathway is a critical early response mechanism of the host that detects
pathogens, initiates the production of inflammatory cytokines, and recruits effector cells to …

A quadruplex qRT-PCR for differential detection of four porcine enteric coronaviruses

H Zhou, K Shi, F Long, K Zhao, S Feng, Y Yin… - Veterinary …, 2022 - mdpi.com
Simple Summary Porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus
(TGEV), porcine deltacoronavirus (PDCoV), and swine acute diarrhea syndrome …

Prediction and verification of curcumin as a potential drug for inhibition of pdcov replication in llc-pk1 cells

X Wang, X Wang, J Zhang, Q Shan, Y Zhu… - International Journal of …, 2023 - mdpi.com
Porcine deltacoronavirus (PDCoV) is an emerging swine enteropathogenic coronavirus
(CoV) that causes lethal watery diarrhea in neonatal pigs and poses economic and public …

Porcine enteric coronavirus PEDV induces the ROS-ATM and Caspase7-CAD-γH2AX Signaling pathways to Foster its replication

X Ming, H Chen, Y Yang, P Zhao, L Sun, C Zhang… - Viruses, 2022 - mdpi.com
DNA damage response (DDR) is an evolutionarily conserved mechanism by which
eukaryotic cells sense DNA lesions caused by intrinsic and extrinsic stimuli, including virus …