[HTML][HTML] Myocarditis and inflammatory cardiomyopathy: current evidence and future directions

C Tschöpe, E Ammirati, B Bozkurt… - Nature Reviews …, 2021 - nature.com
Inflammatory cardiomyopathy, characterized by inflammatory cell infiltration into the
myocardium and a high risk of deteriorating cardiac function, has a heterogeneous …

Reappraising the role of inflammation in heart failure

L Adamo, C Rocha-Resende, SD Prabhu… - Nature Reviews …, 2020 - nature.com
The observation that heart failure with reduced ejection fraction is associated with elevated
circulating levels of pro-inflammatory cytokines opened a new area of research that has …

[HTML][HTML] Spatial multi-omic map of human myocardial infarction

C Kuppe, RO Ramirez Flores, Z Li, S Hayat… - Nature, 2022 - nature.com
Myocardial infarction is a leading cause of death worldwide. Although advances have been
made in acute treatment, an incomplete understanding of remodelling processes has limited …

Inflammation in Heart Failure: JACC State-of-the-Art Review

SP Murphy, R Kakkar, CP McCarthy… - Journal of the American …, 2020 - jacc.org
It has long been observed that heart failure (HF) is associated with measures of systemic
inflammation. In recent years, there have been significant advancements in our …

Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction

SA Dick, JA Macklin, S Nejat, A Momen… - Nature …, 2019 - nature.com
Macrophages promote both injury and repair after myocardial infarction, but discriminating
functions within mixed populations remains challenging. Here we used fate mapping …

Cardiac monocytes and macrophages after myocardial infarction

C Peet, A Ivetic, DI Bromage… - Cardiovascular research, 2020 - academic.oup.com
Improvements in early interventions after acute myocardial infarction (AMI), notably, the
increased use of timely reperfusion therapy, have increased survival dramatically in recent …

Cardioimmunology: the immune system in cardiac homeostasis and disease

FK Swirski, M Nahrendorf - Nature Reviews Immunology, 2018 - nature.com
The past few decades have generated growing recognition that the immune system makes
an important contribution to cardiac development, composition and function. Immune cells …

The biological basis for cardiac repair after myocardial infarction: from inflammation to fibrosis

SD Prabhu, NG Frangogiannis - Circulation research, 2016 - Am Heart Assoc
In adult mammals, massive sudden loss of cardiomyocytes after infarction overwhelms the
limited regenerative capacity of the myocardium, resulting in the formation of a collagen …

Brain–heart interaction: cardiac complications after stroke

Z Chen, P Venkat, D Seyfried, M Chopp, T Yan… - Circulation …, 2017 - Am Heart Assoc
Neurocardiology is an emerging specialty that addresses the interaction between the brain
and the heart, that is, the effects of cardiac injury on the brain and the effects of brain injury …

Inflammation–cause or consequence of heart failure or both?

S Van Linthout, C Tschöpe - Current heart failure reports, 2017 - Springer
Abstract Purpose of Review With the intention to summarize the currently available evidence
on the pathophysiological relevance of inflammation in heart failure, this review addresses …