It is an urgent need that defect repair can develop from simple device fixation to living tissue
reconstruction, from short life function replacement to permanent regeneration repair. At …

Mesenchymal stem cells (MSCs) have been widely applied to regenerative medicine owing
to their multiple differentiation, selfrenewal, and immunomodulatory abilities. Exosomes are …

Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …

Exosomes are extracellular vesicles formed by various donor cells that regulate gene
expression and cellular function in recipient cells. Exosomes derived from mesenchymal …

Exosomes are the small extracellular vesicles secreted by cells for intercellular
communication. Exosomes are rich in therapeutic cargos such as microRNA (miRNA), long …

Distinctive characteristics of articular cartilage such as avascularity and low chondrocyte
conversion rate present numerous challenges for orthopedists. Tissue engineering is a …

Osteoarthritis (OA) is characterized by progressive cartilage degeneration with increasing
prevalence and unsatisfactory treatment efficacy. Exosomes derived from mesenchymal …

Osteoarthritis (OA), a common cause of chronic articular cartilage degeneration, is the main
cause of disability in older adults and severely affects quality of life. Multiple factors are …

Tendon and ligament injury poses an increasingly large burden to society. This systematic
review explores whether mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) …

Biomaterials and pertaining formulations have been very successful in various diagnostic
and therapeutic applications because of its ability to overcome pharmacological limitations …