Signaling pathways of chronic kidney diseases, implications for therapeutics

Q Yuan, B Tang, C Zhang - Signal transduction and targeted therapy, 2022 - nature.com
Chronic kidney disease (CKD) is a chronic renal dysfunction syndrome that is characterized
by nephron loss, inflammation, myofibroblasts activation, and extracellular matrix (ECM) …

Understanding the diversity of membrane lipid composition

T Harayama, H Riezman - Nature reviews Molecular cell biology, 2018 - nature.com
Cellular membranes are formed from a chemically diverse set of lipids present in various
amounts and proportions. A high lipid diversity is universal in eukaryotes and is seen from …

Lipid metabolism reprogramming and its potential targets in cancer

C Cheng, F Geng, X Cheng, D Guo - Cancer communications, 2018 - Springer
Reprogramming of lipid metabolism is a newly recognized hallmark of malignancy.
Increased lipid uptake, storage and lipogenesis occur in a variety of cancers and contribute …

Flipping the metabolic switch: understanding and applying the health benefits of fasting

SD Anton, K Moehl, WT Donahoo, K Marosi, SA Lee… - …, 2018 - Wiley Online Library
Objective Intermittent fasting (IF) is a term used to describe a variety of eating patterns in
which no or few calories are consumed for time periods that can range from 12 hours to …

Edible insects: An alternative of nutritional, functional and bioactive compounds

AJ da Silva Lucas, LM de Oliveira, M Da Rocha… - Food chemistry, 2020 - Elsevier
The ingestion of insects has become a new trend in food science approximately since 2013,
when the Food and Agriculture Organization of the United Nations (FAO) published a …

Potential mechanisms of bisphenol A (BPA) contributing to human disease

I Cimmino, F Fiory, G Perruolo, C Miele… - International journal of …, 2020 - mdpi.com
Bisphenol A (BPA) is an organic synthetic compound serving as a monomer to produce
polycarbonate plastic, widely used in the packaging for food and drinks, medical devices …

Short-and medium-chain fatty acids in energy metabolism: the cellular perspective

P Schönfeld, L Wojtczak - Journal of lipid research, 2016 - ASBMB
Short-and medium-chain fatty acids (SCFAs and MCFAs), independently of their cellular
signaling functions, are important substrates of the energy metabolism and anabolic …

Changes in plasma free fatty acids associated with type-2 diabetes

A IS Sobczak, C A. Blindauer, A J. Stewart - Nutrients, 2019 - mdpi.com
Type 2 diabetes mellitus (T2DM) is associated with increased total plasma free fatty acid
(FFA) concentrations and an elevated risk of cardiovascular disease. The exact mechanisms …

Effect of ethanol on lipid metabolism

M You, GE Arteel - Journal of hepatology, 2019 - Elsevier
Hepatic lipid metabolism is a series of complex processes that control influx and efflux of not
only hepatic lipid pools, but also organismal pools. Lipid homeostasis is usually tightly …

New insights into the pathophysiology of dyslipidemia in type 2 diabetes

MR Taskinen, J Borén - Atherosclerosis, 2015 - Elsevier
Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality for
patients with type 2 diabetes, despite recent significant advances in management strategies …