Application of metal coordination chemistry to explore and manipulate cell biology
KL Haas, KJ Franz - Chemical reviews, 2009 - ACS Publications
Our desire to understand how the individual molecules that make up cells organize, interact,
and communicate to form living systems has led to the burgeoning field of chemical biology …
and communicate to form living systems has led to the burgeoning field of chemical biology …
Cancer biomarkers-current perspectives
In the recent years, knowledge about cancer biomarkers has increased tremendously
providing great opportunities for improving the management of cancer patients by …
providing great opportunities for improving the management of cancer patients by …
Microsatellites in different eukaryotic genomes: survey and analysis
We examined the abundance of microsatellites with repeated unit lengths of 1–6 base pairs
in several eukaryotic taxonomic groups: primates, rodents, other mammals, nonmammalian …
in several eukaryotic taxonomic groups: primates, rodents, other mammals, nonmammalian …
Crystal structure of Δ-[Ru(bpy)2dppz]2+ bound to mismatched DNA reveals side-by-side metalloinsertion and intercalation
H Song, JT Kaiser, JK Barton - Nature chemistry, 2012 - nature.com
DNA mismatches represent a novel target in the development of diagnostics and
therapeutics for cancer, because deficiencies in DNA mismatch repair are implicated in …
therapeutics for cancer, because deficiencies in DNA mismatch repair are implicated in …
Analysis of microsatellites in major crops assessed by computational and experimental approaches
L Gao, J Tang, H Li, J Jia - Molecular Breeding, 2003 - Springer
Over 85Mb publicly available expressed sequence tags (ESTs) from four agronomically
important crops were used to search for the types and frequencies of simple sequence …
important crops were used to search for the types and frequencies of simple sequence …
DNA replication fidelity and cancer
BD Preston, TM Albertson, AJ Herr - Seminars in cancer biology, 2010 - Elsevier
Cancer is fueled by mutations and driven by adaptive selection. Normal cells avoid
deleterious mutations by replicating their genomes with extraordinary accuracy. Here we …
deleterious mutations by replicating their genomes with extraordinary accuracy. Here we …
Oxidative stress inactivates the human DNA mismatch repair system
CL Chang, G Marra, DP Chauhan… - … of Physiology-Cell …, 2002 - journals.physiology.org
In the human DNA mismatch repair (MMR) system, hMSH2 forms the hMutSα and hMutSβ
complexes with hMSH6 and hMSH3, respectively, whereas hMLH1 and hPMS2 form the …
complexes with hMSH6 and hMSH3, respectively, whereas hMLH1 and hPMS2 form the …
Atherosclerosis and cancer: common molecular pathways of disease development and progression
JS Ross, NE Stagliano, MJ Donovan… - Annals of the New …, 2001 - Wiley Online Library
Recently, a series of shared molecular pathways have emerged that have in common a
significant role in the pathogenesis and progression of both atherosclerosis and cancer …
significant role in the pathogenesis and progression of both atherosclerosis and cancer …
Immunotherapy and immunotherapy combinations in metastatic castration-resistant prostate cancer
D Bansal, MA Reimers, EM Knoche, RK Pachynski - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapy has changed the treatment paradigm of numerous
malignancies such as non-small cell lung cancer and melanoma. To date, there has been …
malignancies such as non-small cell lung cancer and melanoma. To date, there has been …
DNA mismatch repair genes and colorectal cancer
JMD Wheeler, WF Bodmer, NJMC Mortensen - Gut, 2000 - gut.bmj.com
Positional cloning and linkage analysis have shown that inactivation of one of the mismatch
repair genes (hMLH1, hMSH2, hPMS1, hPMS2, GTBP/hMSH6) is responsible for the …
repair genes (hMLH1, hMSH2, hPMS1, hPMS2, GTBP/hMSH6) is responsible for the …