Our desire to understand how the individual molecules that make up cells organize, interact,
and communicate to form living systems has led to the burgeoning field of chemical biology …

In the recent years, knowledge about cancer biomarkers has increased tremendously
providing great opportunities for improving the management of cancer patients by …

We examined the abundance of microsatellites with repeated unit lengths of 1–6 base pairs
in several eukaryotic taxonomic groups: primates, rodents, other mammals, nonmammalian …

DNA mismatches represent a novel target in the development of diagnostics and
therapeutics for cancer, because deficiencies in DNA mismatch repair are implicated in …

Over 85Mb publicly available expressed sequence tags (ESTs) from four agronomically
important crops were used to search for the types and frequencies of simple sequence …

Cancer is fueled by mutations and driven by adaptive selection. Normal cells avoid
deleterious mutations by replicating their genomes with extraordinary accuracy. Here we …

In the human DNA mismatch repair (MMR) system, hMSH2 forms the hMutSα and hMutSβ
complexes with hMSH6 and hMSH3, respectively, whereas hMLH1 and hPMS2 form the …

Recently, a series of shared molecular pathways have emerged that have in common a
significant role in the pathogenesis and progression of both atherosclerosis and cancer …

Simple Summary Immunotherapy has changed the treatment paradigm of numerous
malignancies such as non-small cell lung cancer and melanoma. To date, there has been …

Positional cloning and linkage analysis have shown that inactivation of one of the mismatch
repair genes (hMLH1, hMSH2, hPMS1, hPMS2, GTBP/hMSH6) is responsible for the …