Extracellular vesicles in liquid biopsies as biomarkers for solid tumors

B Irmer, S Chandrabalan, L Maas, A Bleckmann… - Cancers, 2023 - mdpi.com
Simple Summary During the past decade, liquid biopsy-related publications have increased
exponentially, demonstrating the great potential of screening body fluids for diagnosis …

Exosome nanovesicles as potential biomarkers and immune checkpoint signaling modulators in lung cancer microenvironment: recent advances and emerging …

NA Khan, M Asim, KH Biswas, AN Alansari… - Journal of Experimental …, 2023 - Springer
Lung cancer remains the leading cause of cancer-related deaths globally, and the survival
rate remains low despite advances in diagnosis and treatment. The progression of lung …

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles

U Erdbrügger, CJ Blijdorp, IV Bijnsdorp… - Journal of …, 2021 - Wiley Online Library
Urine is commonly used for clinical diagnosis and biomedical research. The discovery of
extracellular vesicles (EV) in urine opened a new fast‐growing scientific field. In the last …

Rapid capture of cancer extracellular vesicles by lipid patch microarrays

HY Liu, R Kumar, C Zhong, S Gorji… - Advanced …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) contain various bioactive molecules such as DNA, RNA, and
proteins, and play a key role in the regulation of cancer progression. Furthermore, cancer …

Liquid biopsy: a family of possible diagnostic tools

B Michela - Diagnostics, 2021 - mdpi.com
Liquid biopsies could be considered an excellent diagnostic tool, in different physiological or
pathological conditions. The possibility of using liquid biopsies for non-invasive clinical …

Uptake and fate of extracellular membrane vesicles: nucleoplasmic reticulum-associated late endosomes as a new gate to intercellular communication

D Corbeil, MF Santos, J Karbanová, T Kurth, G Rappa… - Cells, 2020 - mdpi.com
Extracellular membrane vesicles (EVs) are emerging as new vehicles in intercellular
communication, but how the biological information contained in EVs is shared between cells …

Immune regulation by dendritic cell extracellular vesicles in cancer immunotherapy and vaccines

I Fernández-Delgado, D Calzada-Fraile… - Cancers, 2020 - mdpi.com
Simple Summary Dendritic cells have a central role in starting and regulating immune
functions in anticancer responses. The crosstalk of dendritic cells with tumors and other …

Communication in tiny packages: exosomes as means of tumor-stroma communication

J Daßler-Plenker, V Küttner, M Egeblad - Biochimica et Biophysica Acta …, 2020 - Elsevier
Tumor-derived exosomes are nano-sized vesicles acting as multi-signal devices influencing
tumor growth at local and distant sites. Exosomes are derived from the endolysosomal …

Myeloid cell modulation by tumor-derived extracellular vesicles

I Arkhypov, S Lasser, V Petrova, R Weber… - International journal of …, 2020 - mdpi.com
Extracellular vesicles (EV) can carry proteins, RNA and DNA, thus serving as
communication tools between cells. Tumor cells secrete EV, which can be taken up by …

Exosomes: from garbage bins to translational medicine

Y Liu, Y Wang, Q Lv, X Li - International journal of pharmaceutics, 2020 - Elsevier
Exosomes are lipid bilayer-enclosed vesicles of endosomal origin, which initially considered
as garbage bins to dispose unwanted cellular components, but they are now emerged as an …