Metastatic heterogeneity of breast cancer: Molecular mechanism and potential therapeutic targets

Y Liang, H Zhang, X Song, Q Yang - Seminars in cancer biology, 2020 - Elsevier
Breast cancer is one of the most common malignancies among women throughout the world
and is the major cause of most cancer-related deaths. Several explanations account for the …

[HTML][HTML] Cellular uptake and retention of nanoparticles: Insights on particle properties and interaction with cellular components

R Augustine, A Hasan, R Primavera, RJ Wilson… - Materials Today …, 2020 - Elsevier
The utilization of nanomaterials in the biological and medical field is quickly progressing,
particularly in areas where traditional diagnostics and treatment approaches have limited …

Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment

Y Dai, C Xu, X Sun, X Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
Nanovehicles can efficiently carry and deliver anticancer agents to tumour sites. Compared
with normal tissue, the tumour microenvironment has some unique properties, such as …

[HTML][HTML] Current approaches of photothermal therapy in treating cancer metastasis with nanotherapeutics

L Zou, H Wang, B He, L Zeng, T Tan, H Cao, X He… - Theranostics, 2016 - ncbi.nlm.nih.gov
Cancer metastasis accounts for the high mortality of many types of cancer. Owing to the
unique advantages of high specificity and minimal invasiveness, photothermal therapy (PTT) …

Liposomes coated with isolated macrophage membrane can target lung metastasis of breast cancer

H Cao, Z Dan, X He, Z Zhang, H Yu, Q Yin, Y Li - ACS nano, 2016 - ACS Publications
Cancer metastasis leads to high mortality of breast cancer and is difficult to treat because of
the poor delivery efficiency of drugs. Herein, we report the wrapping of a drug-carrying …

Breast cancer lung metastasis: Molecular biology and therapeutic implications

L Jin, B Han, E Siegel, Y Cui, A Giuliano… - Cancer biology & …, 2018 - Taylor & Francis
Distant metastasis accounts for the vast majority of deaths in patients with cancer. Breast
cancer exhibits a distinct metastatic pattern commonly involving bone, liver, lung, and brain …

Photoactivatable organic semiconducting pro-nanoenzymes

J Li, J Huang, Y Lyu, J Huang, Y Jiang… - Journal of the …, 2019 - ACS Publications
Therapeutic enzymes hold great promise for cancer therapy; however, in vivo remote control
of enzymatic activity to improve their therapeutic specificity remains challenging. This study …

[HTML][HTML] Drug resistance in metastatic breast cancer: tumor targeted nanomedicine to the rescue

V Gote, AR Nookala, PK Bolla, D Pal - International journal of molecular …, 2021 - mdpi.com
Breast cancer, specifically metastatic breast, is a leading cause of morbidity and mortality in
women. This is mainly due to relapse and reoccurrence of tumor. The primary reason for …

Preferential targeting cerebral ischemic lesions with cancer cell-inspired nanovehicle for ischemic stroke treatment

W He, Q Mei, J Li, Y Zhai, Y Chen, R Wang, E Lu… - Nano Letters, 2021 - ACS Publications
The poor drug delivery to cerebral ischemic regions is a key challenge of ischemic stroke
treatment. Inspired by the intriguing blood–brain barrier (BBB)-penetrating ability of 4T1 …

Tumour microenvironment responsive nanoconstructs for cancer theranostic

A Gulzar, J Xu, C Wang, F He, D Yang, S Gai, P Yang… - Nano today, 2019 - Elsevier
The tumour mass is made up of not only of a heterogeneous population of cancer cells
nonetheless also a mixture of resident as well as the infiltrating host cells, secreted factors …