[HTML][HTML] Identification of the functions and prognostic values of RNA binding proteins in bladder cancer
Y Wu, Z Liu, X Wei, H Feng, B Hu, B Liu, Y Luan… - Frontiers in …, 2021 - frontiersin.org
Post-transcriptional regulation plays a leading role in gene regulation and RNA binding
proteins (RBPs) are the most important posttranscriptional regulatory protein. RBPs had …
proteins (RBPs) are the most important posttranscriptional regulatory protein. RBPs had …
[HTML][HTML] Drug delivery approaches for HuR-targeted therapy for lung cancer
Lung cancer (LC) is often diagnosed at an advanced stage and conventional treatments for
disease management have limitations associated with them. Novel therapeutic targets are …
disease management have limitations associated with them. Novel therapeutic targets are …
iASPP suppression mediates terminal UPR and improves BRAF-inhibitor sensitivity of colon cancers
S Zheng, X Wang, H Liu, D Zhao, Q Lin… - Cell Death & …, 2023 - nature.com
Unfolded protein response (UPR) signaling is activated under endoplasmic reticulum (ER)
stress, an emerging cancer hallmark, leading to either adaptive survival or cell death, while …
stress, an emerging cancer hallmark, leading to either adaptive survival or cell death, while …
Small molecule targeting CELF1 RNA-binding activity to control HSC activation and liver fibrosis
Y Tan, X Sun, Y Xu, B Tang, S Xu, D Lu… - Nucleic Acids …, 2022 - academic.oup.com
CUGBP Elav-like family member 1 (CELF1), an RNA-binding protein (RBP), plays important
roles in the pathogenesis of diseases such as myotonic dystrophy, liver fibrosis and cancers …
roles in the pathogenesis of diseases such as myotonic dystrophy, liver fibrosis and cancers …
[HTML][HTML] Comparative transcriptomics analyses in livers of mice, humans, and humanized mice define human-specific gene networks
Mouse is the most widely used animal model in biomedical research, but it remains
unknown what causes the large number of differentially regulated genes between human …
unknown what causes the large number of differentially regulated genes between human …
[HTML][HTML] Transcriptomic and proteomic analysis reveals the potential role of RBMS1 in adipogenesis and adipocyte metabolism
G Dairi, S Al Mahri, H Benabdelkamel… - International Journal of …, 2023 - mdpi.com
Adipocytes play a critical role in maintaining a healthy systemic metabolism by storing and
releasing energy in the form of fat and helping to regulate glucose and lipid levels in the …
releasing energy in the form of fat and helping to regulate glucose and lipid levels in the …
[HTML][HTML] The emerging role and promise of circular RNAs in obesity and related metabolic disorders
M Zaiou - Cells, 2020 - mdpi.com
Circular RNAs (circRNAs) are genome transcripts that are produced from back-splicing of
specific regions of pre-mRNA. These single-stranded RNA molecules are widely expressed …
specific regions of pre-mRNA. These single-stranded RNA molecules are widely expressed …
[HTML][HTML] A landscape of murine long non-coding RNAs reveals the leading transcriptome alterations in adipose tissue during aging
Aging is an inevitable process that involves profound physiological changes. Long non-
coding RNAs (lncRNAs) are emerging as important regulators in various biological …
coding RNAs (lncRNAs) are emerging as important regulators in various biological …
Palmitic Acid–Induced Long Noncoding RNA PARAIL Regulates Inflammation via Interaction With RNA-Binding Protein ELAVL1 in Monocytes and Macrophages
Background: Obesity and diabetes are associated with elevated free fatty acids like palmitic
acid (PA), which promote chronic inflammation and impaired inflammation resolution …
acid (PA), which promote chronic inflammation and impaired inflammation resolution …
[HTML][HTML] Role of hsa_circ_0000280 in regulating vascular smooth muscle cell function and attenuating neointimal hyperplasia via ELAVL1
Z Wang, H Wang, C Guo, F Yu, Y Zhang, L Qiao… - Cellular and Molecular …, 2023 - Springer
The pathological proliferation of cells in vascular smooth muscle underlies neointimal
hyperplasia (NIH) development during atherosclerosis. Circular RNAs (circRNAs), which …
hyperplasia (NIH) development during atherosclerosis. Circular RNAs (circRNAs), which …