Raman spectroscopy is a very powerful tool for material analysis, allowing for exploring the
properties of a wide range of different materials. Since its discovery, Raman spectroscopy …

Hyperspectral imaging (HSI) is an emerging imaging modality for medical applications,
especially in disease diagnosis and image-guided surgery. HSI acquires a three …

Historically, the screening of patients for signs of oral cancer and precancerous lesions has
relied upon the conventional oral examination. A variety of commercial diagnostic aids and …

Early identification of high-risk disease could greatly reduce both mortality and morbidity due
to oral cancer. We describe a simple handheld device that facilitates the direct visualization …

This article presents an overview of time-resolved (lifetime) fluorescence techniques used in
biomedical diagnostics. In particular, we review the development of time-resolved …

In cancer surgery, intra-operative assessment of the tumor-free margin, which is critical for
the prognosis of the patient, relies on the visual appearance and palpation of the tumor …

Purpose: Genetically altered cells could become widespread across the epithelium of
patients with oral cancer, often in clinically and histologically normal tissue, and contribute to …

Hyperspectral imaging (HSI) is an emerging imaging modality for medical applications,
especially in disease diagnosis and image-guided surgery. HSI acquires three-dimensional …

Autofluorescence spectroscopy and imaging have been studied for the early detection and
classification of (pre) malignancies of the oral mucosa. In the present review we will give an …

Purpose: Autofluorescence imaging is increasingly used to noninvasively identify neoplastic
oral cavity lesions. Improving the diagnostic accuracy of these techniques requires a better …