Intermittent hypoxemia and OSA: implications for comorbidities

NA Dewan, FJ Nieto, VK Somers - Chest, 2015 - Elsevier
OSA is a common chronic disorder that is associated with significant morbidity and mortality
including cardiovascular, metabolic, and neurocognitive disease and increased cancer …

Pathophysiology of sleep apnea

JA Dempsey, SC Veasey, BJ Morgan… - Physiological …, 2010 - journals.physiology.org
Sleep-induced apnea and disordered breathing refers to intermittent, cyclical cessations or
reductions of airflow, with or without obstructions of the upper airway (OSA). In the presence …

[HTML][HTML] CPAP, weight loss, or both for obstructive sleep apnea

JA Chirinos, I Gurubhagavatula, K Teff… - … England Journal of …, 2014 - Mass Medical Soc
Background Obesity and obstructive sleep apnea tend to coexist and are associated with
inflammation, insulin resistance, dyslipidemia, and high blood pressure, but their causal …

Sleep disorders and sleep deprivation: an unmet public health problem

BM Altevogt, HR Colten - 2006 - books.google.com
Clinical practice related to sleep problems and sleep disorders has been expanding rapidly
in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and …

Effects of poor and short sleep on glucose metabolism and obesity risk

K Spiegel, E Tasali, R Leproult… - Nature Reviews …, 2009 - nature.com
The importance of sleep to hormones and glucose metabolism was first documented more
than four decades ago. Since then, sleep curtailment has become an endemic behavior in …

Sleep loss: a novel risk factor for insulin resistance and Type 2 diabetes

K Spiegel, K Knutson, R Leproult… - Journal of applied …, 2005 - journals.physiology.org
Chronic sleep loss as a consequence of voluntary bedtime restriction is an endemic
condition in modern society. Although sleep exerts marked modulatory effects on glucose …

Role of sleep quality in the metabolic syndrome

D Koren, M Dumin, D Gozal - Diabetes, metabolic syndrome and …, 2016 - Taylor & Francis
Emerging evidence has assigned an important role to sleep as a modulator of metabolic
homeostasis. The impact of variations in sleep duration, sleep-disordered breathing, and …

[HTML][HTML] Management of diabesity: Current concepts

M Michaelidou, JM Pappachan… - World Journal of …, 2023 - ncbi.nlm.nih.gov
The global prevalence of obesity is increasing rapidly with an exponential rise in incidence
of type 2 diabetes mellitus in recent years.'Diabesity', the term coined to show the strong …

Association of sleep-disordered breathing and the occurrence of stroke

M Arzt, T Young, L Finn, JB Skatrud… - American journal of …, 2005 - atsjournals.org
Rationale: Sleep-disordered breathing has been linked to stroke in previous studies.
However, these studies either used surrogate markers of sleep-disordered breathing or …

Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities

WT McNicholas, MR Bonsignore… - European …, 2007 - Eur Respiratory Soc
Considerable evidence is available in support of an independent association between
obstructive sleep apnoea syndrome (OSAS) and cardiovascular disease, which is …