Does obesity play a major role in the pathogenesis of sleep apnoea and its associated manifestations via inflammation, visceral adiposity, and insulin resistance?

AN Vgontzas - Archives of physiology and biochemistry, 2008 - Taylor & Francis
Despite the early recognition of the strong association between obstructive sleep apnoea
(OSA) and obesity, and OSA and cardiovascular problems, sleep apnoea has been treated …

Relationships between sleep disordered breathing and glucose metabolism in polycystic ovary syndrome

E Tasali, E Van Cauter… - The Journal of Clinical …, 2006 - academic.oup.com
Context: Women with polycystic ovary syndrome (PCOS) are insulin resistant and are at
increased risk for sleep apnea, which, in turn, may contribute to insulin resistance. Objective …

Obesity and obstructive sleep apnea in children

R Tauman, D Gozal - Paediatric respiratory reviews, 2006 - Elsevier
The prevalence and severity of obesity in children and adolescent is dramatically increasing
worldwide with a corresponding increase in the prevalence of obesity-associated …

A randomised controlled trial of nasal continuous positive airway pressure on insulin sensitivity in obstructive sleep apnoea

JCM Lam, B Lam, TJ Yao, AYK Lai… - European …, 2010 - Eur Respiratory Soc
The effects of treatment of obstructive sleep apnoea (OSA) on glucose metabolism have
been investigated previously with conflicting results. This study evaluated the impact of …

Insulin resistance and daytime sleepiness in patients with sleep apnoea

A Barceló, F Barbe, M de la Peña, P Martinez… - Thorax, 2008 - thorax.bmj.com
Background: Excessive daytime sleepiness (EDS), obesity and insulin resistance (IR) occur
frequently in patients with obstructive sleep apnoea syndrome (OSAS). We hypothesised …

Noninvasive ventilation in mild obesity hypoventilation syndrome: a randomized controlled trial

JC Borel, R Tamisier, J Gonzalez-Bermejo, JP Baguet… - Chest, 2012 - Elsevier
Objective Open studies suggest that treatment of obesity hypoventilation syndrome (OHS) by
noninvasive ventilation (NIV) restores sleep quality and daytime vigilance and reduces …

Obstructive sleep apnea-hypopnea syndrome

EJ Olson, WR Moore, TI Morgenthaler, PC Gay… - Mayo Clinic …, 2003 - Elsevier
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is characterized by repetitive
episodes of airflow reduction (hypopnea) or cessation (apnea) due to upper airway collapse …

The reciprocal interaction between obesity and obstructive sleep apnoea

CW Ong, DM O'Driscoll, H Truby, MT Naughton… - Sleep medicine …, 2013 - Elsevier
Obesity is a significant risk factor in the pathogenesis of obstructive sleep apnoea (OSA)
altering airway anatomy and collapsibility, and respiratory control. The association between …

Sleep Apnea and Commercial Motor Vehicle Operators:: Statement From the Joint Task Force of the American College of Chest Physicians, American College of …

N Hartenbaum, N Collop, IM Rosen… - … of occupational and …, 2006 - journals.lww.com
M edical research supports the finding that obstructive sleep apnea (OSA) is a significant
cause of motor vehicle crashes (MVCs) resulting in two-to sevenfold increased risk. 1–6 …

Adipose tissue in obesity and obstructive sleep apnoea

MR Bonsignore, WT McNicholas… - European …, 2012 - Eur Respiratory Soc
A European Respiratory Society research seminar on “Metabolic alterations in obstructive
sleep apnoea (OSA)” was jointly organised in October 2009 together with two EU COST …