Chronic inflammation: key player and biomarker-set to predict and prevent cancer development and progression based on individualized patient profiles

S Qian, O Golubnitschaja, X Zhan - Epma Journal, 2019 - Springer
A strong relationship exists between tumor and inflammation, which is the hot point in cancer
research. Inflammation can promote the occurrence and development of cancer by …

[HTML][HTML] Trends in the disease burden of HBV and HCV infection in China from 1990-2019

T Yue, Q Zhang, T Cai, M Xu, H Zhu… - International Journal of …, 2022 - Elsevier
Objectives This study aimed to reveal the 30-year dynamics of hepatitis B virus (HBV) and
hepatitis C virus (HCV) disease burden in China from 1990-2019. Methods HBV/HCV data …

Drug repurposing for viral cancers: A paradigm of machine learning, deep learning, and virtual screening‐based approaches

F Ahmed, IS Kang, KH Kim, A Asif… - Journal of Medical …, 2023 - Wiley Online Library
Cancer management is major concern of health organizations and viral cancers account for
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …

Human organs-on-chips for virology

H Tang, Y Abouleila, L Si, AM Ortega-Prieto… - Trends in …, 2020 - cell.com
While conventional in vitro culture systems and animal models have been used to study the
pathogenesis of viral infections and to facilitate development of vaccines and therapeutics …

Revisiting hepatitis B virus: challenges of curative therapies

J Hu, U Protzer, A Siddiqui - Journal of virology, 2019 - Am Soc Microbiol
With a yearly death toll of 880,000, hepatitis B virus (HBV) remains a major health problem
worldwide, despite an effective prophylactic vaccine and well-tolerated, effective antivirals …

Historical perspective on the discovery of the quasispecies concept

E Domingo, C García-Crespo… - Annual review of …, 2021 - annualreviews.org
Viral quasispecies are dynamic distributions of nonidentical but closely related mutant and
recombinant viral genomes subjected to a continuous process of genetic variation …

Antitumor effects of fecal microbiota transplantation: Implications for microbiome modulation in cancer treatment

H Xu, C Cao, Y Ren, S Weng, L Liu, C Guo… - Frontiers in …, 2022 - frontiersin.org
Fecal microbiome transplantation (FMT) from healthy donors is one of the techniques for
restoration of the dysbiotic gut, which is increasingly being used to treat various diseases …

Caution regarding the specificities of pan-cancer microbial structure

A Gihawi, CS Cooper, DS Brewer - Microbial genomics, 2023 - microbiologyresearch.org
Results published in an article by Poore et al.(Nature. 2020; 579: 567–574) suggested that
machine learning models can almost perfectly distinguish between tumour types based on …

Identification of key pathways and genes in the dynamic progression of HCC based on WGCNA

L Yin, Z Cai, B Zhu, C Xu - Genes, 2018 - mdpi.com
Hepatocellular carcinoma (HCC) is a devastating disease worldwide. Though many efforts
have been made to elucidate the process of HCC, its molecular mechanisms of …

Current trends and challenges in point-of-care urinalysis of biomarkers in trace amounts

S Yeasmin, G Ammanath, A Onder, E Yan… - TrAC Trends in …, 2022 - Elsevier
Urinalysis enables non-invasive point-of-care (POC) testing of numerous biomarkers at their
physiological and elevated levels, obviating the need for sophisticated equipment or trained …