Genetic mechanisms of fertilization failure and early embryonic arrest: a comprehensive review

Y Wei, J Wang, R Qu, W Zhang, Y Tan… - Human …, 2024 - academic.oup.com
BACKGROUND Infertility and pregnancy loss are longstanding problems. Successful
fertilization and high-quality embryos are prerequisites for an ongoing pregnancy. Studies …

mtDNA regulates cGAS-STING signaling pathway in adenomyosis

K Wang, Y Wen, X Fu, S Wei, S Liu, M Chen - Free Radical Biology and …, 2024 - Elsevier
In various hyperproliferative disorders, damaged mitochondria can release mitochondrial
DNA (mtDNA) into the cytoplasm, activating the cGAS-STING signaling pathway and …

Mitochondrial DNA Supplementation of Oocytes Has Downstream Effects on the Transcriptional Profiles of Sus scrofa Adult Tissues with High mtDNA Copy Number

T Okada, A Penn, JC St. John - International Journal of Molecular …, 2023 - mdpi.com
Oocytes can be supplemented with extra copies of mitochondrial DNA (mtDNA) to enhance
developmental outcome. Pigs generated through supplementation with mtDNA derived from …

Identification of Potential Metabolomic, Small Non-Coding RNA and Vaginal Microbiome Biomarkers of Reproductive Potential in Gilts and Sows Using Machine …

L Fletcher - 2024 - atrium.lib.uoguelph.ca
The reproductive performance of female pigs in the breeding herd is vital for production
efficiency in the pork industry. Current selection protocols may be improved by applying …