Oxidative stress regulation and related metabolic pathways in epithelial–mesenchymal transition of breast cancer stem cells
Epithelial–mesenchymal transition (EMT) is a cell remodeling process in which epithelial
cells undergo a reversible phenotype switch via the loss of adhesion capacity and …
cells undergo a reversible phenotype switch via the loss of adhesion capacity and …
Extracellular vesicle-mediated chemoresistance in oral squamous cell carcinoma
Oral Squamous Cell Carcinoma (OSCC) remains a cancer with poor prognosis and high
recurrence rate. Even with multimodal treatment options available for OSCC, tumor drug …
recurrence rate. Even with multimodal treatment options available for OSCC, tumor drug …
Hyperglycaemia induces metabolic reprogramming into a glycolytic phenotype and promotes epithelial-mesenchymal transitions via YAP/TAZ-Hedgehog signalling …
Z Liu, H Hayashi, K Matsumura, Y Ogata… - British Journal of …, 2023 - nature.com
Background Hyperglycaemia is a well-known initial symptom in patients with pancreatic
ductal adenocarcinoma (PDAC). Metabolic reprogramming in cancer, described as the …
ductal adenocarcinoma (PDAC). Metabolic reprogramming in cancer, described as the …
[HTML][HTML] Decreased expression of HADH is related to poor prognosis and immune infiltration in kidney renal clear cell carcinoma
H Jiang, H Chen, P Wan, N Chen - Genomics, 2021 - Elsevier
Kidney renal clear cell carcinoma (KIRC) is the subtype pf kidney cancer having the highest
mortality as well as the highest potential of invasion and metastasis. The expression of …
mortality as well as the highest potential of invasion and metastasis. The expression of …
AUP1 regulates lipid metabolism and induces lipid accumulation to accelerate the progression of renal clear cell carcinoma
C Chen, W Zhao, X Lu, Y Ma, P Zhang, Z Wang… - Cancer …, 2022 - Wiley Online Library
Lipid metabolic reprogramming is a prominent feature of clear cell renal cell carcinoma
(ccRCC). Lipid accumulation affects cellular energy homeostasis, biofilm synthesis, lipid …
(ccRCC). Lipid accumulation affects cellular energy homeostasis, biofilm synthesis, lipid …
Glutamine-fructose-6-phosphate transaminase 2 (GFPT2) Is upregulated in breast epithelial–mesenchymal transition and responds to oxidative stress
Q Wang, ST Karvelsson, A Kotronoulas… - Molecular & Cellular …, 2022 - ASBMB
Breast cancer cells that have undergone partial epithelial–mesenchymal transition (EMT)
are believed to be more invasive than cells that have completed EMT. To study metabolic …
are believed to be more invasive than cells that have completed EMT. To study metabolic …
[HTML][HTML] Investigation of the effects of downregulation of jumping translocation breakpoint (JTB) protein expression in MCF7 cells for potential use as a biomarker in …
MCF7 is a commonly used luminal type A non-invasive/poor-invasive human breast cancer
cell line that does not usually migrate or invade compared with MDA-MB-231 highly …
cell line that does not usually migrate or invade compared with MDA-MB-231 highly …
Crosstalk between immune checkpoint modulators, metabolic reprogramming and cellular plasticity in triple-negative breast cancer
A Poddar, SR Rao, P Prithviraj, G Kannourakis… - Current …, 2022 - mdpi.com
Breast cancer is one of the major causes of mortality in women worldwide. Accounting for 15–
20% of all breast cancer diagnoses, the triple-negative breast cancer (TNBC) subtype …
20% of all breast cancer diagnoses, the triple-negative breast cancer (TNBC) subtype …
Biological and clinical impacts of glucose metabolism in pancreatic ductal adenocarcinoma
Z Liu, H Hayashi, K Matsumura, N Uemura, Y Shiraishi… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma is a lethal cancer with high metastatic
properties. While surgical treatment is considered the first choice, the difficulty associated …
properties. While surgical treatment is considered the first choice, the difficulty associated …
UDP‐glucose dehydrogenase expression is upregulated following EMT and differentially affects intracellular glycerophosphocholine and acetylaspartate levels in …
Q Wang, ST Karvelsson, F Johannsson… - Molecular …, 2022 - Wiley Online Library
Metabolic rewiring is one of the indispensable drivers of epithelial–mesenchymal transition
(EMT) involved in breast cancer metastasis. In this study, we explored the metabolic …
(EMT) involved in breast cancer metastasis. In this study, we explored the metabolic …