Axonal regeneration and formation of tripartite (axo-glial) junctions at damaged sites is a
prerequisite for early repair of injured spinal cord. Transplantation of stem cells at such sites …

Glycosaminoglycans (GAGs) are an important component of the extracellular matrix as they
influence cell behavior and have been sought for tissue regeneration, biomaterials, and …

Over the past few decades, microglial cells have been regarded as the main executor of
inflammation after acute and chronic central nervous system (CNS) disorders, responding …

Astrogliosis has a very dynamic response during the progression of spinal cord injury, with
beneficial or detrimental effects on recovery. It is therefore important to develop strategies to …

There is increasing interest in defining the location, content, and role of extracellular matrix
(ECM) components in brain structure and function during development, aging, injury, and …

Traumatic spinal cord injury (SCI) can cause severe neurological impairments. Clinically
available treatments are quite limited, with unsatisfactory remediation effects. Residing …

The fluid‐filled cystic cavity sealed by a dense scar developed following traumatic spinal
cord injury (SCI) has been a major obstacle to neural regeneration and functional recovery …

Among the many molecules that contribute to glial scarring, chondroitin sulfate
proteoglycans (CSPGs) are known to be potent inhibitors of neuronal regeneration …

Oligodendrocyte progenitor cells (OPCs) are the most proliferative and dispersed population
of progenitor cells in the adult central nervous system, which allows these cells to rapidly …

Astrocytes are the main support cells of the central nervous system. They also participate in
neuroimmune reactions. In response to pathological and immune stimuli, astrocytes …