Radiotherapy is a key pillar of solid cancer treatment. Despite high level of conformal dose
deposition, radiotherapy is limited due to co-irradiation of organs-at risk and subsequent …

Glioblastoma multiforme (GBM) is the most common primary brain cancer in adults with poor
prognosis. Despite the current state of knowledge on its genetic characteristics, relatively …

Background Considering the strong attenuation of photons and the potential to increase the
deposition of radiation, high-atomic number nanomaterials are often used as …

Radiation therapy (RT) has the capacity to induce immunogenic death in tumor cells,
thereby potentially inducing in situ vaccination (ISV) to prime systemic antitumor immune …

A significant amount of progress in nanotechnology has been made due to the development
of engineered nanoparticles. The use of metallic nanoparticles for various biomedical …

Radiosensitizers are compounds or nanostructures, which can improve the efficiency of
ionizing radiation to kill cells. Radiosensitization increases the susceptibility of cancer cells …

Purpose This study aimed to evaluate the radiosensitizing potential of Au@ DTDTPA (Gd)
nanoparticles when combined with conventional external X-ray irradiation (RT) to treat GBM …

The efficacy of immunoradiotherapy consisting of radiation therapy and immune checkpoint
blockade relies on effectively promoting the systemic antitumor immune response's …

Lung cancer is listed as one of the hotfooted malignancies on the basis of mortality and
morbidity. Thus, emergence of new targeting and immunotherapies is being recognized that …

Abstract Purpose Radiotherapy-activated NBTXR3 (NBTXR3+ RT) has demonstrated
superior efficacy in cancer cell destruction and tumor growth control, compared to …