Innate and adaptive immunity: the understudied driving force of heart valve disease
F Bartoli-Leonard, J Zimmer… - Cardiovascular research, 2021 - academic.oup.com
Calcific aortic valve disease (CAVD), and its clinical manifestation that is calcific aortic valve
stenosis, is the leading cause for valve disease within the developed world, with no current …
stenosis, is the leading cause for valve disease within the developed world, with no current …
[HTML][HTML] The role of macrophages in aortic dissection
X Wang, H Zhang, L Cao, Y He, A Ma… - Frontiers in physiology, 2020 - frontiersin.org
Aortic dissection (AD) is a fatal disease that accounts for a large proportion of aortic-related
deaths and has an incidence of about 3–4 per 100,000 individuals every year. Recent …
deaths and has an incidence of about 3–4 per 100,000 individuals every year. Recent …
The role of interleukin-10 family members in cardiovascular diseases
S Xu, J Zhang, J Liu, J Ye, Y Xu, Z Wang, J Yu… - International …, 2021 - Elsevier
Abstract Interleukin (IL)-10 cytokine family members, including IL-10, IL-19, IL-20, IL-22, IL-
24, IL-26 and the distantly related IL-28A, IL-28B, and IL-29, play critical roles in the …
24, IL-26 and the distantly related IL-28A, IL-28B, and IL-29, play critical roles in the …
Research progress on the pathogenesis of aortic dissection
ZQ Yin, H Han, X Yan, QJ Zheng - Current problems in cardiology, 2023 - Elsevier
Aortic dissection is a critical cardiovascular disease due to the separation of media and
adventitia caused by the rupture of vascular wall intima. The disease has a high mortality …
adventitia caused by the rupture of vascular wall intima. The disease has a high mortality …
Role of necroptosis and immune infiltration in human stanford type A aortic dissection: Novel insights from bioinformatics analyses
F Liu, T Wei, L Liu, F Hou, C Xu, H Guo… - Oxidative medicine …, 2022 - Wiley Online Library
Background. Stanford type A aortic dissection (TAAD) is one of the most life‐threatening
cardiovascular emergencies with high mortality and morbidity, and necroptosis is a newly …
cardiovascular emergencies with high mortality and morbidity, and necroptosis is a newly …
[HTML][HTML] The role of inflammation and myeloperoxidase-related oxidative stress in the pathogenesis of genetically triggered thoracic aortic aneurysms
C Malecki, BD Hambly, RW Jeremy… - International Journal of …, 2020 - mdpi.com
Genetically triggered thoracic aortic aneurysms (TAAs) are usually considered to exhibit
minimal levels of inflammation. However, emerging data demonstrate that specific features …
minimal levels of inflammation. However, emerging data demonstrate that specific features …
Circulating Th1, Th2, Th9, Th17, Th22, and Treg levels in aortic dissection patients
J Ye, Y Wang, Z Wang, Q Ji, Y Huang… - Mediators of …, 2018 - Wiley Online Library
Background. Previous studies demonstrated that the subsets of CD4+ T helper (Th) cells are
closely related to vascular diseases, including atherosclerosis and hypertension. This study …
closely related to vascular diseases, including atherosclerosis and hypertension. This study …
Cytokines in aortic dissection
T Zeng, L Shi, Q Ji, Y Shi, Y Huang, YU Liu, J Gan… - Clinica chimica acta, 2018 - Elsevier
Aortic dissection (AD) is one of the most dangerous forms of vascular disease, characterized
by endometrial rupture and intramural hematoma formation. Generally, the pathological …
by endometrial rupture and intramural hematoma formation. Generally, the pathological …
[HTML][HTML] Single-cell RNA-Seq analysis reveals macrophages are involved in the pathogenesis of human sporadic acute type A aortic dissection
B Zhang, K Zeng, RC Guan, HQ Jiang, YJ Qiang… - Biomolecules, 2023 - mdpi.com
Macrophages play an important role in the progression of sporadic acute type A aortic
dissection (ATAAD). The aim of this study was to characterize the cellular heterogeneity of …
dissection (ATAAD). The aim of this study was to characterize the cellular heterogeneity of …
Relationship between inflammatory-related cytokines with aortic dissection
J Song, H Peng, M Lai, H Kang, X Chen… - International …, 2023 - Elsevier
Aortic dissection, characterized by severe intramural hematoma formation and acute
endometrial rupture, is caused by excessive bleeding within the aortic wall or a severe tear …
endometrial rupture, is caused by excessive bleeding within the aortic wall or a severe tear …