[HTML][HTML] Hepatic macrophages in liver homeostasis and diseases-diversity, plasticity and therapeutic opportunities
Macrophages, which are key cellular components of the liver, have emerged as essential
players in the maintenance of hepatic homeostasis and in injury and repair processes in …
players in the maintenance of hepatic homeostasis and in injury and repair processes in …
[HTML][HTML] Beyond hemostasis: platelet innate immune interactions and thromboinflammation
J Mandel, M Casari, M Stepanyan, A Martyanov… - International journal of …, 2022 - mdpi.com
There is accumulating evidence that platelets play roles beyond their traditional functions in
thrombosis and hemostasis, eg, in inflammatory processes, infection and cancer, and that …
thrombosis and hemostasis, eg, in inflammatory processes, infection and cancer, and that …
[HTML][HTML] How we treat primary immune thrombocytopenia in adults
X Liu, Y Hou, M Hou - Journal of Hematology & Oncology, 2023 - Springer
Primary immune thrombocytopenia (ITP) is an immune-mediated bleeding disorder
characterized by decreased platelet counts and an increased risk of bleeding. Multiple …
characterized by decreased platelet counts and an increased risk of bleeding. Multiple …
The interplay between PEGylated nanoparticles and blood immune system
C Guo, H Yuan, Y Wang, Y Feng, Y Zhang, T Yin… - Advanced Drug Delivery …, 2023 - Elsevier
During the last two decades, an increasing number of reports have pointed out that the
immunogenicity of polyethylene glycol (PEG) may trigger accelerated blood clearance …
immunogenicity of polyethylene glycol (PEG) may trigger accelerated blood clearance …
[HTML][HTML] Endocrine role of bone in the regulation of energy metabolism
Abstracts Bone mainly functions as a supportive framework for the whole body and is the
major regulator of calcium homeostasis and hematopoietic function. Recently, an increasing …
major regulator of calcium homeostasis and hematopoietic function. Recently, an increasing …
[HTML][HTML] Platelet activation mechanisms and consequences of immune thrombocytopenia
Autoimmune disorders are often associated with low platelet count or thrombocytopenia. In
immune-induced thrombocytopenia (IIT), a common mechanism is increased platelet …
immune-induced thrombocytopenia (IIT), a common mechanism is increased platelet …
[HTML][HTML] The phagocytic code regulating phagocytosis of mammalian cells
TOJ Cockram, JM Dundee, AS Popescu… - Frontiers in …, 2021 - frontiersin.org
Mammalian phagocytes can phagocytose (ie eat) other mammalian cells in the body if they
display certain signals, and this phagocytosis plays fundamental roles in development, cell …
display certain signals, and this phagocytosis plays fundamental roles in development, cell …
[HTML][HTML] Crosstalk between platelets and microbial pathogens
Platelets, small anucleate cells circulating in the blood, are critical mediators in haemostasis
and thrombosis. Interestingly, recent studies demonstrated that platelets contain both pro …
and thrombosis. Interestingly, recent studies demonstrated that platelets contain both pro …
[HTML][HTML] Kupffer cell receptor CLEC4F is important for the destruction of desialylated platelets in mice
The liver has recently been identified as a major organ for destruction of desialylated
platelets. However, the underlying mechanism remains unclear. Kupffer cells, which are …
platelets. However, the underlying mechanism remains unclear. Kupffer cells, which are …
Functional vulnerability of liver macrophages to capsules defines virulence of blood-borne bacteria
Many encapsulated bacteria use capsules to cause invasive diseases. However, it remains
largely unknown how the capsules enhance bacterial virulence under in vivo infection …
largely unknown how the capsules enhance bacterial virulence under in vivo infection …