Polyphenols (PPs) are a large group of phytochemicals containing phenolic rings with two or
more hydroxyl groups. They possess powerful antioxidant properties, multiple therapeutic …

Polyphenols have long been recognized as health-promoting entities, including beneficial
effects on cardiovascular disease, but their reputation has been boosted recently following a …

Current pharmacological treatments of atherosclerosis often target either cholesterol control
or inflammation management, to inhibit atherosclerotic progression, but cannot lead to direct …

Cardiac damage and vascular dysfunction due to underlying diseases, such as
hypertension and cardiac thrombosis, or side effects from certain drugs may lead to critical …

The endothelium, as the guardian of vascular homeostasis, is closely related to the
occurrence and development of cardiovascular diseases (CVDs). As an early marker of the …

Atherosclerosis is the basic pathological process of many diseases, such as coronary
atherosclerosis and stroke. Nutrients can affect the occurrence and development of …

Myeloperoxidase (MPO) exhibits a unique property to use H2O2 to oxidize chloride and lead
to the generation of a strong oxidant, hypochlorous acid (HOCl), which plays important roles …

Myeloperoxidase (MPO)-dependent hypochlorous acid (HOCl) generation plays crucial
roles in diabetic vascular complications. As a natural polyphenol, quercetin has antioxidant …

Cardiovascular diseases (CVD) are the leading causes of global death, increasing over
time. Despite current novel improvements, it is still a major medical challenge. Quercetin …

Background: Epidemiological studies have suggested that a regular intake of flavonoids is
beneficial for cellular homeostasis and in the prevention of the transformation of normal cells …