Fundamentals and developments in fluorescence-guided cancer surgery

JSD Mieog, FB Achterberg, A Zlitni… - Nature reviews Clinical …, 2022 - nature.com
Fluorescence-guided surgery using tumour-targeted imaging agents has emerged over the
past decade as a promising and effective method of intraoperative cancer detection. An …

Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging

HW Liu, L Chen, C Xu, Z Li, H Zhang… - Chemical Society …, 2018 - pubs.rsc.org
Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …

Progress and perspective of solid-state organic fluorophores for biomedical applications

K Li, TB Ren, S Huan, L Yuan… - Journal of the American …, 2021 - ACS Publications
Fluorescent organic dyes have been extensively used as raw materials for the development
of versatile imaging tools in the field of biomedicine. Particularly, the development of solid …

An “AND” Molecular Logic Gate as a Super‐Enhancers for De Novo Designing Activatable Probe and Its Application in Atherosclerosis Imaging

M Sang, Y Huang, L Wang, L Chen… - Advanced …, 2023 - Wiley Online Library
Developing activatable fluorescent probes with superlative fluorescence enhancement
factor (F/F0) to improve the signal‐to‐noise (S/N) ratio is still an urgent issue.“AND” …

Molecular imaging: design mechanism and bioapplications

L Chen, Y Lyu, X Zhang, L Zheng, Q Li, D Ding… - Science China …, 2023 - Springer
Molecular imaging is a non-invasive method to image and analyze the concentration and
activity of functional biomolecules in cells or in vivo at molecular level, and plays an …

A de novo strategy to develop NIR precipitating fluorochrome for long-term in situ cell membrane bioimaging

K Li, Y Lyu, Y Huang, S Xu, HW Liu… - Proceedings of the …, 2021 - National Acad Sciences
Cell membrane–targeted bioimaging is a prerequisite for studying the roles of membrane-
associated biomolecules in various physiological and pathological processes. However …

Fluorescent probes for the detection of alkaline phosphatase in biological systems: Recent advances and future prospects

K Wang, W Wang, XY Zhang, AQ Jiang… - TrAC Trends in …, 2021 - Elsevier
Alkaline phosphatase (ALP), an important enzyme in living organisms, plays significant roles
in the hydrolysis of phosphate groups from nucleic acids, proteins, and other substrates …

Protein@ cyanine‐based NIR‐II lymphography enables the supersensitive visualization of lymphedema and tumor lymphatic metastasis

J Xu, Y Du, T Han, N Zhu, S Zhu - Advanced Healthcare …, 2023 - Wiley Online Library
Visualization of the lymphatic system is clinically indispensable for the diagnosis and/or
treatment of lymphatic diseases. Although indocyanine green (ICG) lymphography becomes …

[HTML][HTML] Peptides for optical medical imaging and steps towards therapy

M Staderini, A Megia-Fernandez, K Dhaliwal… - Bioorganic & medicinal …, 2018 - Elsevier
Optical medical imaging is a rapidly growing area of research and development that offers a
multitude of healthcare solutions both diagnostically and therapeutically. In this review …

Lipid‐Activatable Fluorescent Probe for Intraoperative Imaging of Atherosclerotic Plaque Using In Situ Patch

J Zheng, S Zhao, Y Mao, Z Du, G Li, M Sang - Small, 2022 - Wiley Online Library
The surgical removal of lesions is among the most common and effective treatments for
atherosclerosis. It is often the only curative treatment option, and the ability to visualize the …