Global epidemiology of gout: prevalence, incidence, treatment patterns and risk factors

M Dehlin, L Jacobsson, E Roddy - Nature Reviews Rheumatology, 2020 - nature.com
Gout is the most common inflammatory arthritis and occurs when hyperuricaemia, sustained
elevation of serum urate levels resulting in supersaturation of body tissues with urate, leads …

Global epidemiology of gout: prevalence, incidence and risk factors

CF Kuo, MJ Grainge, W Zhang, M Doherty - Nature reviews …, 2015 - nature.com
Gout is a crystal-deposition disease that results from chronic elevation of uric acid levels
above the saturation point for monosodium urate (MSU) crystal formation. Initial presentation …

Association between gout flare and subsequent cardiovascular events among patients with gout

E Cipolletta, LJ Tata, G Nakafero, AJ Avery, MA Mamas… - Jama, 2022 - jamanetwork.com
Importance Gout is associated with cardiovascular diseases. The temporal association
between gout flares and cardiovascular events has not been investigated. Objective To …

[HTML][HTML] Impact of comorbidities on gout and hyperuricaemia: an update on prevalence and treatment options

T Bardin, P Richette - BMC medicine, 2017 - Springer
Gout, the most prevalent inflammatory arthritis worldwide, is associated with cardiovascular
and renal diseases, and is an independent predictor of premature death. The frequencies of …

Excess comorbidities in gout: the causal paradigm and pleiotropic approaches to care

HK Choi, N McCormick, C Yokose - Nature Reviews Rheumatology, 2022 - nature.com
Gout is a common hyperuricaemic metabolic condition that leads to painful inflammatory
arthritis and a high comorbidity burden, especially cardiometabolic-renal (CMR) conditions …

[HTML][HTML] Efficacy and cost-effectiveness of nurse-led care involving education and engagement of patients and a treat-to-target urate-lowering strategy versus usual …

M Doherty, W Jenkins, H Richardson, A Sarmanova… - The Lancet, 2018 - thelancet.com
Background In the UK, gout management is suboptimum, with only 40% of patients receiving
urate-lowering therapy, usually without titration to achieve a target serum urate …

The role of neutrophil extracellular traps in rheumatic diseases

F Apel, A Zychlinsky, EF Kenny - Nature Reviews Rheumatology, 2018 - nature.com
Rheumatic diseases are a collection of disorders defined by the presence of inflammation
and destruction of joints and internal organs. A common feature of these diseases is the …

Incident myocardial infarction associated with major types of arthritis in the general population: a systematic review and meta-analysis

O Schieir, C Tosevski, RH Glazier… - Annals of the …, 2017 - ard.bmj.com
Objective To synthesise, quantify and compare risks for incident myocardial infarction (MI)
across five major types of arthritis in population-based studies. Methods A systematic search …

Prevalence of hyperuricemia and its associated factors in the general Korean population: an analysis of a population-based nationally representative sample

Y Kim, J Kang, GT Kim - Clinical rheumatology, 2018 - Springer
Hyperuricemia is not only a risk factor for gout but also an independent determinant of
hypertension, diabetes, and chronic kidney diseases. Although the incidence of gout in …

The rising incidence of gout and the increasing burden of comorbidities: a population-based study over 20 years

MM Elfishawi, N Zleik, Z Kvrgic, CJ Michet… - The Journal of …, 2018 - jrheum.org
Objective. To examine the incidence of gout over the last 20 years and to evaluate possible
changes in associated comorbid conditions. Methods. The medical records were reviewed …