The severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) pandemic has had
devastating effects on global health and worldwide economy. Despite an initial reluctance to …

Modulation of neutrophil recruitment and function is crucial for targeting inflammatory cells to
sites of infection to combat invading pathogens while, at the same time, limiting host tissue …

Background Thrombocytopenia has been implicated in patients infected with severe acute
respiratory syndrome coronavirus 2, while the association of platelet count and changes with …

Acute respiratory distress syndrome (ARDS) is a life-threatening noncardiogenic circulatory
disorder of the lungs associated with critical illnesses such as sepsis, trauma, and immune …

Platelets are among the most abundant cells in the mammalian circulation. Classical platelet
functions in hemostasis and wound healing have been intensively explored and are …

The current coronavirus pandemic, COVID-19, is the third outbreak of disease caused by the
coronavirus family, after Severe Acute Respiratory Syndrome and Middle East Respiratory …

In addition to preserving homeostasis and contributing to immunity, platelets may exhibit a
dysregulated state1, 2 in acute respiratory distress syndrome (ARDS) and potentially …

Thrombocytopenia is a common complication of influenza virus infection, and its severity
predicts the clinical outcome of critically ill patients. The underlying cause (s) remain …

Vascular injury is a well-established, disease-modifying factor in acute respiratory distress
syndrome (ARDS) pathogenesis. Recently, coronavirus disease 2019 (COVID-19)–induced …

Cell-free heme (CFH) is a product of hemoglobin, myoglobin and hemoprotein degradation,
which is a hallmark of pathologies associated with extensive hemolysis and tissue damage …