Lipid rafts as a therapeutic target: thematic review series: biology of lipid rafts

D Sviridov, N Mukhamedova, YI Miller - Journal of lipid research, 2020 - ASBMB
Lipid rafts regulate the initiation of cellular metabolic and signaling pathways by organizing
the pathway components in ordered microdomains on the cell surface. Cellular responses …

High sensitivity quantitative lipidomics analysis of fatty acids in biological samples by gas chromatography–mass spectrometry

O Quehenberger, AM Armando, EA Dennis - Biochimica et Biophysica Acta …, 2011 - Elsevier
Historically considered to be simple membrane components serving as structural elements
and energy storing entities, fatty acids are now increasingly recognized as potent signaling …

Docosahexaenoic acid reduces amyloid β production via multiple pleiotropic mechanisms

MOW Grimm, J Kuchenbecker, S Grösgen… - Journal of Biological …, 2011 - ASBMB
Alzheimer disease is characterized by accumulation of the β-amyloid peptide (Aβ)
generated by β-and γ-secretase processing of the amyloid precursor protein (APP). The …

Docosahexaenoic and eicosapentaenoic acids segregate differently between raft and nonraft domains

JA Williams, SE Batten, M Harris, BD Rockett… - Biophysical journal, 2012 - cell.com
Omega-3 polyunsaturated fatty acids (n-3 PUFA), enriched in fish oils, are increasingly
recognized to have potential benefits for treating many human afflictions. Despite the …

Evaluation of suppressive and pro-resolving effects of EPA and DHA in human primary monocytes and T-helper cells [S]

A Jaudszus, M Gruen, B Watzl, C Ness, A Roth… - Journal of lipid …, 2013 - ASBMB
Despite their beneficial anti-inflammatory properties, eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA) may increase the infection risk at high doses, likely by …

Evaluation of ultraviolet photodissociation tandem mass spectrometry for the structural assignment of unsaturated fatty acid double bond positional isomers

M Fang, Y Rustam, M Palmieri, OM Sieber… - Analytical and …, 2020 - Springer
Fatty acids are a major source of structural diversity within the lipidome due to variations in
their acyl chain lengths, branching, and cyclization, as well as the number, position, and …

[HTML][HTML] PUFA diets alter the microRNA expression profiles in an inflammation rat model

Z Zheng, Y Ge, J Zhang, M Xue… - Molecular …, 2015 - spandidos-publications.com
Abstract Omega‑3 and‑6 polyunsaturated fatty acids (PUFAs) can directly or indirectly
regulate immune homeostasis via inflammatory pathways, and components of these …

Omega‐3 Polyunsaturated Fatty Acids Intake to Regulate Helicobacter pylori‐Associated Gastric Diseases as Nonantimicrobial Dietary Approach

JM Park, M Jeong, EH Kim, YM Han… - BioMed research …, 2015 - Wiley Online Library
Omega‐3 polyunsaturated fatty acids (n‐3 PUFAs), commonly eicosapentaenoic acid (EPA)
and docosahexaenoic acid (DHA), have been acknowledged as essential long‐chain fatty …

Molecular targets of omega 3 and conjugated linoleic fatty acids–“micromanaging” cellular response

F Visioli, E Giordano, NM Nicod, A Dávalos - Frontiers in Physiology, 2012 - frontiersin.org
Essential fatty acids cannot be synthesized de novo by mammals and need to be ingested
either with the diet or through the use of supplements/functional foods to ameliorate …

Impairment of Endogenous Synthesis of Omega-3 DHA Exacerbates T-Cell Inflammatory Responses

E Talamonti, A Jacobsson, V Chiurchiù - International Journal of …, 2023 - mdpi.com
Omega-3 (ω-3) polyunsaturated fatty acids, including docosahexaenoic acid (DHA), are
involved in numerous biological processes and have a range of health benefits. DHA is …