[HTML][HTML] Obesity and bone: a complex relationship

G Rinonapoli, V Pace, C Ruggiero, P Ceccarini… - International journal of …, 2021 - mdpi.com
There is a large literature on the relationship between obesity and bone. What we can
conclude from this review is that the increase in body weight causes an increase in BMD …

Bioactive peptides from food proteins as potential anti-obesity agents: Mechanisms of action and future perspectives

IT Suryaningtyas, JY Je - Trends in Food Science & Technology, 2023 - Elsevier
Background Obesity is a global health concern with limited treatment options due to side
effects and limited efficacy. Bioactive peptides (BAPs) derived from food proteins have …

[HTML][HTML] The role of prunes in modulating inflammatory pathways to improve bone health in postmenopausal women

JJ Damani, MJ De Souza, HL VanEvery, NCA Strock… - Advances in …, 2022 - Elsevier
The prevalence of osteoporosis among women aged 50 y and older is expected to reach
13.6 million by 2030. Alternative nonpharmaceutical agents for osteoporosis, including …

Metabolic interactions between organs in overweight and obesity using total-body positron emission tomography

W Lu, Y Duan, K Li, Z Cheng, J Qiu - International Journal of Obesity, 2024 - nature.com
Abstract Background and Objectives Overweight and obesity is a complex condition
resulting from unbalanced energy homeostasis among various organs. However, systemic …

Understanding osteoporosis: Human bone density, genetic mechanisms, gut microbiota, and future prospects

JJ Ahire, V Kumar, A Rohilla - Probiotics and Antimicrobial Proteins, 2024 - Springer
Osteoporosis is a systemic condition of the skeleton that leads to diminished bone mass, a
breakdown in the bone tissue's microscopic architecture, and an elevated risk of breaking a …

[HTML][HTML] Causal relationship between body mass index, type 2 diabetes and bone mineral density: Mendelian randomization

W Ma, X Zhou, X Huang, Y Xiong - Plos one, 2023 - journals.plos.org
Objective To reveal the relationship between Body Mass Index (BMI), type 2 diabetes, and
bone mineral density (BMD) using a mendelian randomization (MR) approach. Methods …

[HTML][HTML] Understanding the consequences of fatty bone and fatty muscle: how the osteosarcopenic adiposity phenotype uncovers the deterioration of body …

K Hu, E Deya Edelen, W Zhuo, A Khan, J Orbegoso… - Metabolites, 2023 - mdpi.com
Adiposity is central to aging and several chronic diseases. Adiposity encompasses not just
the excess adipose tissue but also body fat redistribution, fat infiltration, hypertrophy of …

Associations between inflammatory mediators and bone outcomes in postmenopausal women: a cross-sectional analysis of baseline data from the prune study

JJ Damani, MJ De Souza, NCA Strock… - Journal of …, 2023 - Taylor & Francis
Purpose Hypoestrogenism triggers increased production of inflammatory mediators, which
contribute to bone loss during postmenopausal osteoporosis. This study aimed to …

[HTML][HTML] A prediction model for osteoporosis risk using a machine-learning approach and its validation in a large cohort

X Wu, S Park - Journal of Korean Medical Science, 2023 - synapse.koreamed.org
Background Osteoporosis develops in the elderly due to decreased bone mineral density
(BMD), potentially increasing bone fracture risk. However, the BMD is not regularly …

High‐Fat Diet Increases Bone Loss by Inducing Ferroptosis in Osteoblasts

RJ Zhu, ZF Wang, Y Xu, HY Wan, X Zhang… - Stem Cells …, 2022 - Wiley Online Library
Current research suggests that chronic high‐fat dietary intake can lead to bone loss in
adults; however, the mechanism by which high‐fat diets affect the development of …