[HTML][HTML] Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution
Thousands of long intervening noncoding RNAs (lincRNAs) have been identified in
mammals. To better understand the evolution and functions of these enigmatic RNAs, we …
mammals. To better understand the evolution and functions of these enigmatic RNAs, we …
Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression
D Chen, H Ju, Y Lu, L Chen, Z Zeng, D Zhang… - Journal of experimental …, 2016 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) have emerged as critical regulators
of tumor progression. However, the role and molecular mechanism of lncRNA XIST in gastric …
of tumor progression. However, the role and molecular mechanism of lncRNA XIST in gastric …
Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs
The recent discovery that the human and other mammalian genomes produce thousands of
long non-coding RNAs (lncRNAs) raises many fascinating questions. These mRNA-like …
long non-coding RNAs (lncRNAs) raises many fascinating questions. These mRNA-like …
Human long non‐coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors
Long non‐coding RNAs (lncRNAs) are a numerous class of newly discovered genes in the
human genome, which have been proposed to be key regulators of biological processes …
human genome, which have been proposed to be key regulators of biological processes …
RNA-sequencing from single nuclei
RV Grindberg, JL Yee-Greenbaum… - Proceedings of the …, 2013 - National Acad Sciences
It has recently been established that synthesis of double-stranded cDNA can be done from a
single cell for use in DNA sequencing. Global gene expression can be quantified from the …
single cell for use in DNA sequencing. Global gene expression can be quantified from the …
Molecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement
Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is an ester of
epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid …
epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid …
Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells
AA Sigova, AC Mullen, B Molinie… - Proceedings of the …, 2013 - National Acad Sciences
Many long noncoding RNA (lncRNA) species have been identified in mammalian cells, but
the genomic origin and regulation of these molecules in individual cell types is poorly …
the genomic origin and regulation of these molecules in individual cell types is poorly …
Long noncoding RNAs regulate adipogenesis
The prevalence of obesity has led to a surge of interest in understanding the detailed
mechanisms underlying adipocyte development. Many protein-coding genes, mRNAs, and …
mechanisms underlying adipocyte development. Many protein-coding genes, mRNAs, and …
Evolutionary dynamics and tissue specificity of human long noncoding RNAs in six mammals
Long intergenic noncoding RNAs (lincRNAs) play diverse regulatory roles in human
development and disease, but little is known about their evolutionary history and constraint …
development and disease, but little is known about their evolutionary history and constraint …
The influence of LINE‐1 and SINE retrotransposons on mammalian genomes
SR Richardson, AJ Doucet, HC Kopera… - Mobile DNA …, 2015 - Wiley Online Library
Transposable elements (TEs) or “jumping genes” historically have been disparaged as a
class of “junk DNA” in mammalian genomes (1, 2). The advent of whole genome DNA …
class of “junk DNA” in mammalian genomes (1, 2). The advent of whole genome DNA …