[HTML][HTML] Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution

I Ulitsky, A Shkumatava, CH Jan, H Sive, DP Bartel - Cell, 2011 - cell.com
Thousands of long intervening noncoding RNAs (lincRNAs) have been identified in
mammals. To better understand the evolution and functions of these enigmatic RNAs, we …

Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression

D Chen, H Ju, Y Lu, L Chen, Z Zeng, D Zhang… - Journal of experimental …, 2016 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) have emerged as critical regulators
of tumor progression. However, the role and molecular mechanism of lncRNA XIST in gastric …

Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs

VA Moran, RJ Perera, AM Khalil - Nucleic acids research, 2012 - academic.oup.com
The recent discovery that the human and other mammalian genomes produce thousands of
long non-coding RNAs (lncRNAs) raises many fascinating questions. These mRNA-like …

Human long non‐coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors

SY Ng, R Johnson, LW Stanton - The EMBO journal, 2012 - embopress.org
Long non‐coding RNAs (lncRNAs) are a numerous class of newly discovered genes in the
human genome, which have been proposed to be key regulators of biological processes …

RNA-sequencing from single nuclei

RV Grindberg, JL Yee-Greenbaum… - Proceedings of the …, 2013 - National Acad Sciences
It has recently been established that synthesis of double-stranded cDNA can be done from a
single cell for use in DNA sequencing. Global gene expression can be quantified from the …

Molecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement

V Aggarwal, HS Tuli, M Tania, S Srivastava… - Seminars in cancer …, 2022 - Elsevier
Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is an ester of
epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid …

Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells

AA Sigova, AC Mullen, B Molinie… - Proceedings of the …, 2013 - National Acad Sciences
Many long noncoding RNA (lncRNA) species have been identified in mammalian cells, but
the genomic origin and regulation of these molecules in individual cell types is poorly …

Long noncoding RNAs regulate adipogenesis

L Sun, LA Goff, C Trapnell… - Proceedings of the …, 2013 - National Acad Sciences
The prevalence of obesity has led to a surge of interest in understanding the detailed
mechanisms underlying adipocyte development. Many protein-coding genes, mRNAs, and …

Evolutionary dynamics and tissue specificity of human long noncoding RNAs in six mammals

S Washietl, M Kellis, M Garber - Genome research, 2014 - genome.cshlp.org
Long intergenic noncoding RNAs (lincRNAs) play diverse regulatory roles in human
development and disease, but little is known about their evolutionary history and constraint …

The influence of LINE‐1 and SINE retrotransposons on mammalian genomes

SR Richardson, AJ Doucet, HC Kopera… - Mobile DNA …, 2015 - Wiley Online Library
Transposable elements (TEs) or “jumping genes” historically have been disparaged as a
class of “junk DNA” in mammalian genomes (1, 2). The advent of whole genome DNA …